BACKGROUND/ PURPOSE: Reproducibility and specificity of the present skin colorimeters is still limited as alterations in erythema can bias the measurement of melanin and vice versa. Here, Dermacatch(®) , a new colorimeter covering the visible light spectrum, has been compared with Mexameter(®) , an established narrow-band reflectance spectrophotometer. METHODS: Repeated measurements with both devices were initially collected on colour charts. Then, measures were compared on 12 human volunteers before and after exposure to UVB, and/or modulation of skin erythema. RESULTS: In vitro sensitivity of Dermacatch to erythema/melanin covered a broader wavelength spectrum than Mexameter while in vivo sensitivity of both devices was similar. Interestingly, Mexameter's melanin and erythema values were falsely affected by an increase in erythema or variation in pigmentation respectively. On the contrary, Dermacatch's melanin and erythema values remained constant in the same circumstances. Furthermore, as Mexameter was at least twice less reproducible than Dermacatch, Mexameter showed an increased risk of a confusion over the detection of erythema or melanin fluctuations. CONCLUSION: The analysis of more than 18,000 measures indicated that, Dermacatch has a significantly higher specificity and reproducibility than Mexameter in the measurement of skin pigmentation and erythema.
BACKGROUND/ PURPOSE: Reproducibility and specificity of the present skin colorimeters is still limited as alterations in erythema can bias the measurement of melanin and vice versa. Here, Dermacatch(®) , a new colorimeter covering the visible light spectrum, has been compared with Mexameter(®) , an established narrow-band reflectance spectrophotometer. METHODS: Repeated measurements with both devices were initially collected on colour charts. Then, measures were compared on 12 human volunteers before and after exposure to UVB, and/or modulation of skin erythema. RESULTS: In vitro sensitivity of Dermacatch to erythema/melanin covered a broader wavelength spectrum than Mexameter while in vivo sensitivity of both devices was similar. Interestingly, Mexameter's melanin and erythema values were falsely affected by an increase in erythema or variation in pigmentation respectively. On the contrary, Dermacatch's melanin and erythema values remained constant in the same circumstances. Furthermore, as Mexameter was at least twice less reproducible than Dermacatch, Mexameter showed an increased risk of a confusion over the detection of erythema or melanin fluctuations. CONCLUSION: The analysis of more than 18,000 measures indicated that, Dermacatch has a significantly higher specificity and reproducibility than Mexameter in the measurement of skin pigmentation and erythema.
Authors: Mirte Langeveld; Lara S van de Lande; Eimear O' Sullivan; Berend van der Lei; Joris A van Dongen Journal: Skin Res Technol Date: 2021-11-09 Impact factor: 2.240
Authors: Corina Danciu; Szilvia Berkó; Gábor Varju; Boglárka Balázs; Lajos Kemény; István Balázs Németh; Andreea Cioca; Alexandra Petruș; Cristina Dehelean; Citu Ioan Cosmin; Elena Amaricai; Claudia Crina Toma Journal: Int J Mol Sci Date: 2015-07-08 Impact factor: 5.923
Authors: Nadja Nicole Zöller; Matthias Hofmann; Manuel Butting; Igor Hrgovic; Jürgen Bereiter-Hahn; August Bernd; Roland Kaufmann; Stefan Kippenberger; Eva Valesky Journal: Indian J Dermatol Date: 2019 Mar-Apr Impact factor: 1.494