Literature DB >> 24033185

Impact of heart magnetic resonance imaging on chelation choices, compliance with treatment and risk of heart disease in patients with thalassaemia major.

Raffaella Origa1, Fabrice Danjou, Stefano Cossa, Gildo Matta, Patrizio Bina, Carlo Dessì, Elisabetta Defraia, Maria L Foschini, Giovanbattista Leoni, Maddalena Morittu, Renzo Galanello.   

Abstract

This study aimed to verify the impact of heart magnetic resonance imaging on chelation choices and patient compliance in a single-institution cohort as well as its predictive value for heart failure and arrhythmias. Abnormal cardiac T2* values determined changes in treatment in most subjects. Heart T2* was confirmed to be highly predictive over 1 year for heart failure and arrhythmias. The choice of chelation regimens known to remove heart iron efficiently was not sufficient by itself to influence the risk. Compliance with treatment had a more remarkable role.
© 2013 John Wiley & Sons Ltd.

Entities:  

Keywords:  arrhythmia; beta thalassaemia major; compliance; heart failure; heart magnetic resonance imaging

Mesh：

Substances：

Year:  2013        PMID： 24033185     DOI： 10.1111/bjh.12517

Source DB:  PubMed          Journal:  Br J Haematol        ISSN： 0007-1048            Impact factor:   6.998


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