Literature DB >> 240331

A critical study on RO-4-1284 antagonism in mice.

F C Colpaert, F M Lenaerts, C J Niemegeers, P A Janssen.   

Abstract

Ro-4-1284 is found to produce ptosis, hypothermia, sedation and miosis in mice, and the antagonsim to these symptoms is investigated. The study reports the differential effects of various pharmacologically distinct classes of compounds. The relevance of this type of experiments to possible antidepressant drug activity is discussed.

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Year:  1975        PMID: 240331

Source DB:  PubMed          Journal:  Arch Int Pharmacodyn Ther        ISSN: 0003-9780


  6 in total

1.  Effects of tetrabenazine and phenylpiperidine analgesics during daily clorgyline treatment.

Authors:  J D Leander
Journal:  Psychopharmacology (Berl)       Date:  1981       Impact factor: 4.530

2.  On the classification of antidepressant drugs.

Authors:  P J Lewi; F C Colpaert
Journal:  Psychopharmacology (Berl)       Date:  1976-09-17       Impact factor: 4.530

Review 3.  The validity of animal models of depression.

Authors:  P Willner
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

4.  A reappraisal of the interaction between tricyclic antidepressants and reserpine-like drugs.

Authors:  P Willner; D Clark
Journal:  Psychopharmacology (Berl)       Date:  1978-06-15       Impact factor: 4.530

5.  The central action of pizotifen.

Authors:  E Przegaliński; L Baran; W Palider; J Siwanowicz
Journal:  Psychopharmacology (Berl)       Date:  1979-04-25       Impact factor: 4.530

Review 6.  Amoxapine: a review of its pharmacology and efficacy in depressed states.

Authors:  S G Jue; G W Dawson; R N Brogden
Journal:  Drugs       Date:  1982-07       Impact factor: 9.546

  6 in total

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