Literature DB >> 24032264

[The role of vitamin D deficiency in the etiology of polycystic ovary syndrome disorders].

Maria Brzozowska1, Agata Karowicz-Bilińska.   

Abstract

Vitamin D deficiency connected with insufficient production in the skin and limited alimentation delivery disrupts the function of all systems of the body and increases the risk of chronic diseases. Many studies have reported associations between low serum 25-hydroxyvitamin D [25(OH)D] level and symptoms of the polycystic ovary syndrome (PCOS) - insulin resistance, hirsutism, and infertility associated with both, ovulatory disorders and abnormal endometrial receptivity. The beneficial effects of vitamin D supplementation on insulin resistance, ovarian follicles maturation, ovulation and menstrual regularity were confirmed. Due to limited evidence, the additional randomized trials are required to establish the correct dose of vitamin D and confirm the effectiveness of vitamin D treatment in PCOS disorders. However; it seems evident that correct supplementation of vitamin D is beneficial in the management of women with PCOS and low 25(OH)D serum levels, and that it could be helpful in improving the effects of PCOS treatment.

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Year:  2013        PMID: 24032264     DOI: 10.17772/gp/1604

Source DB:  PubMed          Journal:  Ginekol Pol        ISSN: 0017-0011            Impact factor:   1.232


  2 in total

1.  The effect of calcium and vitamin D supplementation on menstrual cycle, body mass index and hyperandrogenism state of women with poly cystic ovarian syndrome.

Authors:  Hatav Ghasemi Tehrani; Fatemeh Mostajeran; Somayeh Shahsavari
Journal:  J Res Med Sci       Date:  2014-09       Impact factor: 1.852

Review 2.  Nutrients as novel therapeutic approaches for metabolic disturbances in polycystic ovary syndrome.

Authors:  Asieh Mansour; Saeed Hosseini; Bagher Larijani; Mohammad Reza Mohajeri-Tehrani
Journal:  EXCLI J       Date:  2016-09-05       Impact factor: 4.068

  2 in total

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