Literature DB >> 2403115

Does nondifferential misclassification of exposure always bias a true effect toward the null value?

M Dosemeci1, S Wacholder, J H Lubin.   

Abstract

The authors present some examples to demonstrate that in certain nondifferential misclassification conditions with polychotomous exposure variables, estimates of odds ratios for categories at intermediate level of risk can be biased away from the null or can change direction. In addition, the authors present two examples to demonstrate that the slope of the dose-response trend for the true distributions can change direction, creating a false inverse trend, even if the misclassification is nondifferential.

Mesh:

Year:  1990        PMID: 2403115     DOI: 10.1093/oxfordjournals.aje.a115716

Source DB:  PubMed          Journal:  Am J Epidemiol        ISSN: 0002-9262            Impact factor:   4.897


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