Literature DB >> 24031071

A benign cancer with malicious paraneoplastic syndromes.

Alexander Vogt1, Shuang Wang, Dale Ventour.   

Abstract

A 70-year-old retired general practitioner with known follicular lymphoma presented with ptosis, dysphagia and progressive weakness in his upper and lower limbs. Despite having positive antibodies for myasthenia gravis he did not respond to conventional treatment with pyridostigmine, immunoglobulins and steroids. After 1 week on a general ward, he required intensive care for non-invasive ventilation. On the intensive care unit, he developed a secondary paraneoplastic syndrome in the form of a syndrome of inappropriate antidiuretic hormone secretion and required a tracheostomy for ventilatory support. After 1 week of invasive ventilation and remaining fully conscious throughout, he declined further treatment and passed away.

Entities:  

Mesh:

Year:  2013        PMID: 24031071      PMCID: PMC3794334          DOI: 10.1136/bcr-2013-008883

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  3 in total

1.  The incidence and lifetime prevalence of neurological disorders in a prospective community-based study in the UK.

Authors:  B K MacDonald; O C Cockerell; J W Sander; S D Shorvon
Journal:  Brain       Date:  2000-04       Impact factor: 13.501

Review 2.  Myasthenia gravis, an autoimmune manifestation of lymphoma and lymphoproliferative disorders: case reports and review of literature.

Authors:  Kourosh Rezania; Betty Soliven; Joseph Baron; Helen Lin; Vikram Penumalli; Koen van Besien
Journal:  Leuk Lymphoma       Date:  2011-09-29

Review 3.  The dual association between lymphoma and autoimmunity.

Authors:  M Ehrenfeld; M Abu-Shakra; D Buskila; Y Shoenfeld
Journal:  Blood Cells Mol Dis       Date:  2001 Jul-Aug       Impact factor: 3.039

  3 in total

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