| Literature DB >> 24029604 |
María Sereno1, Gerardo Gutiérrez-Gutiérrez2, César Gómez-Raposo3, Miriam López-Gómez3, Maria Merino-Salvador3, Francisco Zambrana Tébar3, Cristina Rodriguez-Antona4, Enrique Casado5.
Abstract
Oxaliplatin is one of the main drugs used in digestive tumors treatment. Peripheral neuropathy is a well-recognized dose-limiting toxicity of OXL. Two types of neuropathy have been described with this agent: acute or transient and chronic or persistent, with different etiology, clinical manifestations and prognosis. This paper is an exhaustive review about the main aspects of oxaliplatin induced peripheral neuropathy, focus in clinical features, treatment, prevention strategies and future approach.Entities:
Keywords: Digestive tumors; Oxaliplatin; Peripheral neuropathy
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Year: 2013 PMID: 24029604 DOI: 10.1016/j.critrevonc.2013.08.009
Source DB: PubMed Journal: Crit Rev Oncol Hematol ISSN: 1040-8428 Impact factor: 6.312