| Literature DB >> 24028797 |
Saptarshi Das1, Koushik Maharatna.
Abstract
In this paper, an incommensurate fractional order (FO) model has been proposed to generate ECG like waveforms. Earlier investigation of ECG like waveform generation is based on two identical Van-der Pol (VdP) family of oscillators, which are coupled by time delays and gains. In this paper, we suitably modify the three state equations corresponding to the nonlinear cross-product of states, time delay coupling of the two oscillators and low-pass filtering, using the concept of fractional derivatives. Our results show that a wide variety of ECG like waveforms can be simulated from the proposed generalized models, characterizing heart conditions under different physiological conditions. Such generalization of the modelling of ECG waveforms may be useful to understand the physiological process behind ECG signal generation in normal and abnormal heart conditions. Along with the proposed FO models, an optimization based approach is also presented to estimate the VdP oscillator parameters for representing a realistic ECG like signal.Keywords: Delay differential equation (DDE); Electrocardiogram (ECG); Fractional calculus; Phase space; Van-der Pol (VdP) oscillator
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Year: 2013 PMID: 24028797 DOI: 10.1016/j.cmpb.2013.08.012
Source DB: PubMed Journal: Comput Methods Programs Biomed ISSN: 0169-2607 Impact factor: 5.428