Literature DB >> 24028458

The prevalence of vitamin D deficiency and relationship with fracture risk in older women presenting in Australian general practice.

Penelope J Robinson1, Robin J Bell, Alfred Lanzafame, Catherine Kirby, Andrew Weekes, Leon Piterman, Susan R Davis.   

Abstract

AIM: To investigate vitamin D status among older women and to explore relationships between vitamin D and fracture risk and vertebral fractures.
METHODS: A total of 267 general practitioners recruited 2466 women aged >70 years with no known osteoporosis or fragility fracture. Serum 25-hydroxy vitamin D (25(OH)D), bone mineral density by dual-energy X-ray absorptiometry (DXA) and vertebral fracture on thoracolumbar X-ray were determined.
RESULTS: A total of 2368 women, median age 76 years, provided data and of these 13% were on vitamin D supplements. 25(OH)D levels were available for 907 (44.1%) of those not taking vitamin D. 88.3% of these had a level below 75 nmol/L. Serum 25(OH)D was negatively associated with age (P = 0.003) and body mass index (P < 0.001), and positively associated with lower latitude, femoral neck DXA T-score (P = 0.044) and being Caucasian (P < 0.001).
CONCLUSIONS: The vitamin D status of community-dwelling older Australian women is inadequate, yet the use of supplements is low.
© 2011 The Authors. Australasian Journal on Ageing © 2011 ACOTA.

Entities:  

Keywords:  fracture prevention; older people; osteoporosis; vitamin D

Mesh:

Substances:

Year:  2011        PMID: 24028458     DOI: 10.1111/j.1741-6612.2011.00553.x

Source DB:  PubMed          Journal:  Australas J Ageing        ISSN: 1440-6381            Impact factor:   2.111


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