| Literature DB >> 24026617 |
Xiu Ying Qin1, Li Cong Yang, Fang Ling Le, Qian Qian Yu, Dong Dong Sun, Ya Nan Liu, Jie Liu.
Abstract
The crystals of two binuclear copper-based complexes were obtained. One complex can remarkably induce apoptosis and inhibit angiogenesis to mediate tumour growth at a greater extent. Furthermore, this complex showed a strong energy-dependent and non-endocytotic uptake and exhibited multiple anti-cancer functions by inhibiting the expressions of p-Akt and p-Erk1/2 proteins and by decreasing the levels of reactive oxygen species.Entities:
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Year: 2013 PMID： 24026617 DOI： 10.1039/c3dt51548f
Source DB: PubMed Journal: Dalton Trans ISSN： 1477-9226 Impact factor: 4.390