Matthew Daubresse1, Hsien-Yen Chang, Yuping Yu, Shilpa Viswanathan, Nilay D Shah, Randall S Stafford, Stefan P Kruszewski, G Caleb Alexander. 1. *Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health †Center for Drug Safety and Effectiveness, Johns Hopkins University ‡Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD §Division of Health Care Policy and Research, Mayo Clinic, Rochester, MN ∥Program on Prevention Outcomes and Practices, Stanford Prevention Research Center, Stanford University School of Medicine, Palo Alto, CA ¶Stefan P. Kruszewski, MD & Associates, Harrisburg, PA #Department of Mental Health, Johns Hopkins Bloomberg School of Public Health **Department of Medicine, Division of General Internal Medicine, Johns Hopkins Medicine, Baltimore, MD.
Abstract
BACKGROUND: Escalating rates of prescription opioid use and abuse have occurred in the context of efforts to improve the treatment of nonmalignant pain. OBJECTIVE: The aim of the study was to characterize the diagnosis and management of nonmalignant pain in ambulatory, office-based settings in the United States between 2000 and 2010. DESIGN, SETTING, AND PARTICIPANTS: Serial cross-sectional and multivariate regression analyses of the National Ambulatory Medical Care Survey (NAMCS), a nationally representative audit of office-based physician visits, were conducted. MEASURES: (1) Annual visit volume among adults with primary pain symptom or diagnosis; (2) receipt of any pain treatment; and (3) receipt of prescription opioid or nonopioid pharmacologic therapy in visits for new musculoskeletal pain. RESULTS: Primary symptoms or diagnoses of pain consistently represented one-fifth of visits, varying little from 2000 to 2010. Among all pain visits, opioid prescribing nearly doubled from 11.3% to 19.6%, whereas nonopioid analgesic prescribing remained unchanged (26%-29% of visits). One-half of new musculoskeletal pain visits resulted in pharmacologic treatment, although the prescribing of nonopioid pharmacotherapies decreased from 38% of visits (2000) to 29% of visits (2010). After adjusting for potentially confounding covariates, few patient, physician, or practice characteristics were associated with a prescription opioid rather than a nonopioid analgesic for new musculoskeletal pain, and increases in opioid prescribing generally occurred nonselectively over time. CONCLUSIONS: Increased opioid prescribing has not been accompanied by similar increases in nonopioid analgesics or the proportion of ambulatory pain patients receiving pharmacologic treatment. Clinical alternatives to prescription opioids may be underutilized as a means of treating ambulatory nonmalignant pain.
BACKGROUND: Escalating rates of prescription opioid use and abuse have occurred in the context of efforts to improve the treatment of nonmalignant pain. OBJECTIVE: The aim of the study was to characterize the diagnosis and management of nonmalignant pain in ambulatory, office-based settings in the United States between 2000 and 2010. DESIGN, SETTING, AND PARTICIPANTS: Serial cross-sectional and multivariate regression analyses of the National Ambulatory Medical Care Survey (NAMCS), a nationally representative audit of office-based physician visits, were conducted. MEASURES: (1) Annual visit volume among adults with primary pain symptom or diagnosis; (2) receipt of any pain treatment; and (3) receipt of prescription opioid or nonopioid pharmacologic therapy in visits for new musculoskeletal pain. RESULTS: Primary symptoms or diagnoses of pain consistently represented one-fifth of visits, varying little from 2000 to 2010. Among all pain visits, opioid prescribing nearly doubled from 11.3% to 19.6%, whereas nonopioid analgesic prescribing remained unchanged (26%-29% of visits). One-half of new musculoskeletal pain visits resulted in pharmacologic treatment, although the prescribing of nonopioid pharmacotherapies decreased from 38% of visits (2000) to 29% of visits (2010). After adjusting for potentially confounding covariates, few patient, physician, or practice characteristics were associated with a prescription opioid rather than a nonopioid analgesic for new musculoskeletal pain, and increases in opioid prescribing generally occurred nonselectively over time. CONCLUSIONS: Increased opioid prescribing has not been accompanied by similar increases in nonopioid analgesics or the proportion of ambulatory painpatients receiving pharmacologic treatment. Clinical alternatives to prescription opioids may be underutilized as a means of treating ambulatory nonmalignant pain.
Authors: Eija Kalso; Laurie Allan; Paul L I Dellemijn; Clara C Faura; Wilfried K Ilias; Troels S Jensen; Serge Perrot; Leon H Plaghki; Michael Zenz Journal: Eur J Pain Date: 2003 Impact factor: 3.931
Authors: Bridget A Martell; Patrick G O'Connor; Robert D Kerns; William C Becker; Knashawn H Morales; Thomas R Kosten; David A Fiellin Journal: Ann Intern Med Date: 2007-01-16 Impact factor: 25.391
Authors: Richard A Mularski; Foy White-Chu; Devorah Overbay; Lois Miller; Steven M Asch; Linda Ganzini Journal: J Gen Intern Med Date: 2006-06 Impact factor: 5.128
Authors: Brent A Metfessel; Michelle D Mentel; Amy Phanel; Mary Ann Dimartino; Mureen Allen; Samuel Ho Journal: Pharmacoeconomics Date: 2019-03 Impact factor: 4.981
Authors: Andrew H Rogers; Michael F Orr; Justin M Shepherd; Jafar Bakhshaie; Joseph W Ditre; Julia D Buckner; Michael J Zvolensky Journal: J Behav Med Date: 2020-06-27
Authors: Kevin E Vowles; Katie Witkiewitz; Karen J Cusack; Wesley P Gilliam; Karen E Cardon; Sarah Bowen; Karlyn A Edwards; Mindy L McEntee; Robert W Bailey Journal: J Pain Date: 2019-11-21 Impact factor: 5.820
Authors: Brian D Sites; Jordon Harrison; Michael D Herrick; Melissa M Masaracchia; Michael L Beach; Matthew A Davis Journal: Ann Fam Med Date: 2018-01 Impact factor: 5.166
Authors: Taeko Minegishi; Austin B Frakt; Melissa M Garrido; Walid F Gellad; Leslie R M Hausmann; Eleanor T Lewis; Steven D Pizer; Jodie A Trafton; Elizabeth M Oliva Journal: Subst Abus Date: 2019-01-08 Impact factor: 3.716
Authors: Payel Roy; Angela H Jackson; Jeffrey Baxter; Belle Brett; Michael Winter; Ilana Hardesty; Daniel P Alford Journal: Pain Med Date: 2019-04-01 Impact factor: 3.750