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Literature DB >> 24024574

Carrying yourself: self antigen composition of the lymphatic fluid.

Abstract

Advances in proteomics methodology and instrumentation have allowed detailed characterization of the composition of lymph. Far from being a simple ultrafiltrate of blood plasma, lymph has been shown to carry a rich repertoire of proteins and peptides reflecting the tissue of origin and its physiological state. Peptides derived from lymph can be loaded on the MHCII proteins, particularly those present on immature and/or inactivated antigen presenting cells, and may play an important role in maintenance of peripheral tolerance.

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Year: 2013 PMID： 24024574 PMCID： PMC6463995 DOI： 10.1089/lrb.2013.0009

Source DB: PubMed Journal: Lymphat Res Biol ISSN： 1539-6851 Impact factor: 2.589

65 in total

1. Extracellular antigen processing and presentation by immature dendritic cells.

Authors: L Santambrogio; A K Sato; G J Carven; S L Belyanskaya; J L Strominger; L J Stern
Journal: Proc Natl Acad Sci U S A Date: 1999-12-21 Impact factor: 11.205

2. Abundant empty class II MHC molecules on the surface of immature dendritic cells.

Authors: L Santambrogio; A K Sato; F R Fischer; M E Dorf; L J Stern
Journal: Proc Natl Acad Sci U S A Date: 1999-12-21 Impact factor: 11.205

3. Human afferent lymph contains apoptotic cells and "free" apoptotic DNA fragments--can DNA be reutilized by the lymph node cells?

Authors: W L Olszewski
Journal: Lymphology Date: 2001-12 Impact factor: 1.286

Review 4. Reprogramming T cells: the role of extracellular matrix in coordination of T cell activation and migration.

Authors: M L Dustin; A R de Fougerolles
Journal: Curr Opin Immunol Date: 2001-06 Impact factor: 7.486

Review 5. Proteome profiling in body fluids and in cancer cell signaling.

Authors: Elena A Armandola
Journal: MedGenMed Date: 2003-06-05

Review 6. Lysosomal cysteine proteases regulate antigen presentation.

Authors: Karen Honey; Alexander Y Rudensky
Journal: Nat Rev Immunol Date: 2003-06 Impact factor: 53.106

7. The human plasma proteome: a nonredundant list developed by combination of four separate sources.

Authors: N Leigh Anderson; Malu Polanski; Rembert Pieper; Tina Gatlin; Radhakrishna S Tirumalai; Thomas P Conrads; Timothy D Veenstra; Joshua N Adkins; Joel G Pounds; Richard Fagan; Anna Lobley
Journal: Mol Cell Proteomics Date: 2004-01-12 Impact factor: 5.911

Review 8. Travellers in many guises: the origins and destinations of dendritic cells.

Authors: Lois L Cavanagh; Ulrich H Von Andrian
Journal: Immunol Cell Biol Date: 2002-10 Impact factor: 5.126

9. Lymph draining from foot joints in rheumatoid arthritis provides insight into local cytokine and chemokine production and transport to lymph nodes.

Authors: W L Olszewski; J Pazdur; E Kubasiewicz; M Zaleska; C J Cooke; N E Miller
Journal: Arthritis Rheum Date: 2001-03

10. Lipid and apolipoprotein concentrations in prenodal leg lymph of fasted humans. Associations with plasma concentrations in normal subjects, lipoprotein lipase deficiency, and LCAT deficiency.

Authors: M N Nanjee; C J Cooke; W L Olszewski; N E Miller
Journal: J Lipid Res Date: 2000-08 Impact factor: 5.922

4 in total

1. Colonic Insult Impairs Lymph Flow, Increases Cellular Content of the Lymph, Alters Local Lymphatic Microenvironment, and Leads to Sustained Inflammation in the Rat Ileum.

Authors: Walter Cromer; Wei Wang; Scott D Zawieja; Pierre-Yves von der Weid; M Karen Newell-Rogers; David C Zawieja
Journal: Inflamm Bowel Dis Date: 2015-07 Impact factor: 5.325