Generalized peripheral iris transluminance in the pseudoexfoliation syndrome.

Generalized peripheral iris transluminance was investigated in 212 eyes with pseudoexfoliation syndrome (PXS) with or without coexisting glaucoma and in 100 control eyes by the use of a diascleral transilluminator tip. All eyes were blue or blue-gray. Abnormal transluminance was found in 45% of the PXS group and in 18% of the control group (P less than 0.001). The influence of age, PXS without glaucoma, capsular glaucoma, cataracts, and adult-onset diabetes on transluminance was analyzed. The effect of PXS with or without coexisting glaucoma was statistically significant (P less than 0.01) when other factors were adjusted using logistic regression analysis.