Literature DB >> 24023478

Severe hypertension in elapid envenomation.

Ramachandran Meenakshisundaram1, Subramanian Senthilkumaran, Martin Grootveld, Ponniah Thirumalaikolundusubramanian.   

Abstract

Snakebite is not an uncommon medical emergency in India; however, symptoms of autonomic dysfunction in snakebite are rare. The elapid snake envenomation is a frequent occurrence in India, and the krait bite is prevalent in the south Indian region. Here, we present three cases of snakebite with severe hypertension and requiring intravenous nitroglycerin (NTG). As the level of blood pressure (BP) decreased significantly following antisnake venom (ASV) injection in all three cases, it is likely that snake venom-induced dysautonomia might have contributed to severe hypertension in such patients. Clinical and therapeutic challenges of these cases are highlighted, so that practitioners coping with medical emergencies in resource-limited situations can consider snake (krait) bite in the differential diagnosis, and also manage effectively according to corroborative clinical evidences.

Entities:  

Keywords:  Elapid; Hypertension; Krait; Snakebite

Year:  2013        PMID: 24023478      PMCID: PMC3758094          DOI: 10.1016/j.jcdr.2013.02.008

Source DB:  PubMed          Journal:  J Cardiovasc Dis Res        ISSN: 0975-3583


  10 in total

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Authors:  Utkarsh Kohli; Vijeshu Sreedhar
Journal:  Indian Pediatr       Date:  2007-11       Impact factor: 1.411

Review 6.  Neurotoxicity and hypertension following European adder (Vipera berus berus) bites in Hungary: case report and review.

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Journal:  QJM       Date:  2008-07-22

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Journal:  Pharmacol Toxicol       Date:  2002-09

8.  Decreased parasympathetic activities in Malayan krait (Bungarus candidus) envenoming.

Authors:  C Laothong; V Sitprija
Journal:  Toxicon       Date:  2001-09       Impact factor: 3.033

9.  A nationwide study of Vipera berus bites during one year-epidemiology and morbidity of 231 cases.

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Journal:  Clin Toxicol (Phila)       Date:  2006       Impact factor: 4.467

10.  Severe neurotoxic envenoming by the Malayan krait Bungarus candidus (Linnaeus): response to antivenom and anticholinesterase.

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Journal:  Br Med J (Clin Res Ed)       Date:  1983-02-26
  10 in total
  1 in total

1.  Snakebite and severe hypertension: Looking for the Holy Grail.

Authors:  Subramanian Senthilkumaran; Arbid Khamis; Rishya Manikam; Ponniah Thirumalaikolundusubramanian
Journal:  Indian J Crit Care Med       Date:  2014-03
  1 in total

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