Literature DB >> 24023456

Inverted U shaped effect of nicotine on the severity of depressive symptoms: A population-based survey.

Ammar W Ashor1.   

Abstract

OBJECTIVES: To investigate whether that nicotine concentration represented by the degree of smoking dependence variably influence the rate and severity of depressive symptoms.
METHODS: Cross-sectional, analytical study, involving 300 medical students selected by random sampling techniques were asked to complete a questionnaire contains three parts: demographic information, Beck Depression Inventory with cutoff point for depression is 17 and the Fagerström Test for Nicotine dependence with cutoff point for severe dependence is five.
RESULTS: A total of 233 medical students completed the questionnaire; their mean age was (21.38 ± 1.74). The rate of smoking was 22.7% while that of depression was 32.2%. Low dependent smokers in contrast to other groups of smokers and non-smokers display the lowest rate of depressive symptoms (15%), while the highest rate recorded among severely dependent smokers (71.4%, p = 0.0001). After adjustment of other risk factors, regression analysis reveal that severe dependent smokers associated with 12.5 odds of depressive symptoms than non-smokers (p = 0.0001, C.I. 4.10-38.29).
CONCLUSION: In comparison with light and moderate smokers, heavy smokers demonstrate higher risk of depressive symptoms in medical students.

Entities:  

Keywords:  Beck Depression Inventory; Iraq; Medical students; Nicotine dependence; Tobacco smoking

Year:  2013        PMID: 24023456      PMCID: PMC3758084          DOI: 10.1016/j.jyp.2013.06.004

Source DB:  PubMed          Journal:  J Young Pharm        ISSN: 0975-1483


  22 in total

1.  A longitudinal study on the causal association between smoking and depression.

Authors:  Eunjeong Kang; Jaehee Lee
Journal:  J Prev Med Public Health       Date:  2010-05

2.  Monoamine oxidase A binding in the prefrontal and anterior cingulate cortices during acute withdrawal from heavy cigarette smoking.

Authors:  Ingrid Bacher; Sylvain Houle; Xin Xu; Laurie Zawertailo; Alexandra Soliman; Alan A Wilson; Peter Selby; Tony P George; Julia Sacher; Laura Miler; Stephen J Kish; Pablo Rusjan; Jeffrey H Meyer
Journal:  Arch Gen Psychiatry       Date:  2011-08

Review 3.  Biological mechanisms underlying the relationship between stress and smoking: state of the science and directions for future work.

Authors:  Jessica M Richards; Brooke A Stipelman; Marina A Bornovalova; Stacey B Daughters; Rajita Sinha; C W Lejuez
Journal:  Biol Psychol       Date:  2011-07-07       Impact factor: 3.251

Review 4.  Smoking and mental illness.

Authors:  S Leonard; L E Adler; K Benhammou; R Berger; C R Breese; C Drebing; J Gault; M J Lee; J Logel; A Olincy; R G Ross; K Stevens; B Sullivan; R Vianzon; D E Virnich; M Waldo; K Walton; R Freedman
Journal:  Pharmacol Biochem Behav       Date:  2001-12       Impact factor: 3.533

Review 5.  Smoking, nicotine and neuropsychiatric disorders.

Authors:  Peter Dome; Judit Lazary; Miklos Peter Kalapos; Zoltan Rihmer
Journal:  Neurosci Biobehav Rev       Date:  2009-08-07       Impact factor: 8.989

Review 6.  Biological aspects of the link between smoking and depression.

Authors:  E Quattrocki; A Baird; D Yurgelun-Todd
Journal:  Harv Rev Psychiatry       Date:  2000-09       Impact factor: 3.732

7.  Nicotine reverses anhedonic-like response and cognitive impairment in the rat chronic mild stress model of depression: comparison with sertraline.

Authors:  Jesper T Andreasen; Kim Henningsen; Simon Bate; Sofie Christiansen; Ove Wiborg
Journal:  J Psychopharmacol       Date:  2010-12-17       Impact factor: 4.153

8.  Smoking and depression: an examination of mechanisms of comorbidity.

Authors:  Lisa C Dierker; Shelli Avenevoli; Marilyn Stolar; K R Merikangas
Journal:  Am J Psychiatry       Date:  2002-06       Impact factor: 18.112

Review 9.  Nicotine addiction.

Authors:  Neal L Benowitz
Journal:  N Engl J Med       Date:  2010-06-17       Impact factor: 91.245

10.  Usefulness of the Beck Depression Inventory as a screening method for depression among the general population of Finland.

Authors:  Roberto Nuevo; Ville Lehtinen; Patricia M Reyna-Liberato; José Luis Ayuso-Mateos
Journal:  Scand J Public Health       Date:  2009-01       Impact factor: 3.021

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  3 in total

1.  Persistent behavioral effects following early life exposure to retinoic acid or valproic acid in zebrafish.

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Journal:  Neurotoxicology       Date:  2015-10-09       Impact factor: 4.294

2.  Work Stress and Depressive Symptoms in Fishermen With a Smoking Habit: A Mediator Role of Nicotine Dependence and Possible Moderator Role of Expressive Suppression and Cognitive Reappraisal.

Authors:  Hongjuan Jiang; Sailan Li; Juan Yang
Journal:  Front Psychol       Date:  2018-03-26

3.  Protein target identification of ginsenosides in skeletal muscle tissues: discovery of natural small-molecule activators of muscle-type creatine kinase.

Authors:  Feiyan Chen; Kexuan Zhu; Lin Chen; Liufeng Ouyang; Cuihua Chen; Ling Gu; Yucui Jiang; Zhongli Wang; Zixuan Lin; Qiang Zhang; Xiao Shao; Jianguo Dai; Yunan Zhao
Journal:  J Ginseng Res       Date:  2019-03-07       Impact factor: 6.060

  3 in total

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