Literature DB >> 24023328

A rare occurrence of biphasic pulmonary blastoma in an elderly male.

Anand Sharma1, Kieran O'Gorman, Coonar Aman, Doris Rassl, Waria Mohamid, Andreas Polychronis.   

Abstract

Pulmonary Blastoma (PB) is a rare primary lung malignancy usually occurring in young to middle aged adults. Surgery is the primary mode of treatment, but survival is poor with the mean 5-year survival being approximately 16%. We report on a case of PB arising in a 63-year-old man. Computed tomography, magnetic resonance imaging and positron emission tomography confirmed the mass to be of pulmonary origin. The morphological appearance combined with the immunoprofile of the tumour was consistent with a poorly-differentiated biphasic pulmonary blastoma. Two months after the surgical resection the patient relapsed with multiple sites of metastasis. The patient was treated with four cycles of cyclophosphamide-, doxorubicin- and vincristine-(CAV)-based chemotherapy, achieving a partial response to treatment. He is currently on a two-monthly review and is recovering from chemotherapy-related toxicities.

Entities:  

Keywords:  Pulmonary blastoma; elderly; lung malignancy; relapse

Mesh:

Substances:

Year:  2013        PMID: 24023328

Source DB:  PubMed          Journal:  Anticancer Res        ISSN: 0250-7005            Impact factor:   2.480


  6 in total

1.  The Radiologic and Pathologic Diagnosis of Biphasic Pulmonary Blastoma.

Authors:  Fadi Nemeh; Anderson H Kuo; Jenny Ross; Carlos S Restrepo
Journal:  J Radiol Case Rep       Date:  2017-09-30

Review 2.  Classic biphasic pulmonary blastoma with brain and axillary metastases: a case report with molecular analysis and review of literature.

Authors:  Yingjie Xiu; Lili Jiang; Weiping Liu
Journal:  Int J Clin Exp Pathol       Date:  2015-01-01

3.  Pulmonary blastoma: a case report and brief review of the literature of tumor-induced hypoglycemia.

Authors:  Mohammad Reza Mohajeri Tehrani; Ali Ghorbani Abdehgah; Behnam Molavi; Salma Sefidbakht; Ali Reza Maleki; Amir Reza Radmard
Journal:  J Diabetes Metab Disord       Date:  2016-08-15

Review 4.  [Pneumoblastoma in adults: a new case report and literature review].

Authors:  Mustapha Azzakhmam; Fouad Zouaidia; Ahmed Jahidd; Zakia Bernoussi; Kaoutar Znati; Asmae Lakhdissi; Mohamed Bouchikh; Najat Mahassini
Journal:  Pan Afr Med J       Date:  2017-11-02

Review 5.  Classic biphasic pulmonary blastoma: a case report and review of the literature.

Authors:  Zhuanbo Luo; Chao Cao; Ning Xu; Kejing Ying
Journal:  J Int Med Res       Date:  2020-10       Impact factor: 1.671

6.  Pleuropulmonary blastoma, a rare entity in childhood.

Authors:  Pihou Gbande; Tawfiq Abukeshek; Fouad Bensari; Safa El-Kamel
Journal:  BJR Case Rep       Date:  2021-04-29
  6 in total

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