Literature DB >> 24022645

Recurrent Vogt–Koyanagi–Harada disease with sensorineural hearing loss and choroidal thickening.

Akihiro Ishibazawa, Reiko Kinouchi, Yoshiro Minami, Akihiro Katada, Akitoshi Yoshida.   

Abstract

We report a case of Vogt–Koyanagi–Harada (VKH) disease that recurred with sensorineural hearing loss and choroidal thickening. We measured the choroidal thickness using enhanced-depth imaging optical coherence tomography (EDI-OCT) in a patient with VKH during corticosteroid-tapering therapy. A71-year-old male presented with fever, headache, and anorthopia associated with wavy choroidal folds and aserous retinal detachment (SRD). The EDI-OCT images showed choroidal thickening ([600 l m at the subfovea), and he was diagnosed with VKH disease. After treatment with pulsed intravenous methylprednisolone, the choroidal folds and SRD resolved and the choroidal thickness decreased. About 6 months after subsequent treatment with an oral corticosteroid started, headache, tinnitus, and sensorineural hearing loss developed, and increased choroidal thickness was observed without other evidence of increased ocular inflammation. A high-dose corticosteroid was injected and tapered, and the sensorineural hearing loss improved immediately and the choroidal thickness decreased. In the current case, sensorineural hearing loss occurred with recurrent VKH disease;however, there were no ocular inflammatory signs except for rebound choroidal thickening. Measuring the choroidal thickness using EDI-OCT can sensitively identify recurrent VKH disease.

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Year:  2014        PMID: 24022645     DOI: 10.1007/s10792-013-9849-9

Source DB:  PubMed          Journal:  Int Ophthalmol        ISSN: 0165-5701            Impact factor:   2.031


  11 in total

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Review 4.  Pathology of Vogt-Koyanagi-Harada disease.

Authors:  Narsing A Rao
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5.  Sensorineural hearing loss in Vogt-Koyanagi-Harada syndrome.

Authors:  Frank G Ondrey; Eric Moldestad; Mary Ann Mastroianni; Anita Pikus; Daniel Sklare; Estelle Vernon; Robert Nusenblatt; Janine Smith
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9.  Enhanced depth imaging optical coherence tomography of the choroid in Vogt-Koyanagi-Harada disease.

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Review 5.  Optical coherence tomography: A guide to interpretation of common macular diseases.

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6.  Choroidal vascularity index as a biomarker of systemic inflammation in childhood Polyarteritis Nodosa and adenosine deaminase-2 deficiency.

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  6 in total

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