Literature DB >> 24022362

Solitary fibrous tumor of the orbit with multiple cavities.

Matej Polomsky1, Daniel T Sines, Jonathan J Dutton.   

Abstract

Solitary fibrous tumors (SFTs) are rare spindle cell neoplasms of mesenchymal origin that most commonly arise within pleura and have also been reported in many extrapleural sites including the orbit. Cavitary changes within SFT of both pleura and extrapleural sites have been documented, but remain very rare. To the authors' knowledge, the third known case of an orbital solitary fibrous tumor containing large pseudocystic cavities is described. MRI demonstrated a heterogeneous enhancing mass with multiple cavities. Excisional biopsy revealed solid tumor with large cavities filled with straw-colored fluid and tumor cells that stained positive for CD34 and CD99 antigens, consistent with SFT. The patient had an uncomplicated postoperative course with no sign of recurrence and resolution of the proptosis after 12 months of follow up. SFT are rare benign orbital neoplasms that rarely present with cavitary changes. Current treatment options include complete surgical excision, which was performed in this case. Close follow up is advised to monitor for recurrence.

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Mesh:

Year:  2013        PMID: 24022362     DOI: 10.1097/IOP.0b013e318279fdd6

Source DB:  PubMed          Journal:  Ophthalmic Plast Reconstr Surg        ISSN: 0740-9303            Impact factor:   1.746


  4 in total

1.  Orbit Solitary Fibrous Tumor: A Proposed Risk Prediction Model Based on a Case Series and Comprehensive Literature Review.

Authors:  Lester D R Thompson; Sofia S Liou; Kenneth A Feldman
Journal:  Head Neck Pathol       Date:  2020-06-11

Review 2.  A review of solitary fibrous tumours of the orbit and ocular adnexa.

Authors:  Cornelius René; Paolo Scollo; Dominic O'Donovan
Journal:  Eye (Lond)       Date:  2022-07-13       Impact factor: 4.456

Review 3.  Ocular adnexal (orbital) solitary fibrous tumor: nuclear STAT6 expression and literature review.

Authors:  Aleksandra Petrovic; Aurélie Obéric; Alexandre Moulin; Mehrad Hamedani
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2015-03-13       Impact factor: 3.117

4.  Giant cell-rich solitary fibrous tumour of the lacrimal gland with prominent angiomatoid cystic changes and an underlying NAB2ex3-STAT6ex18 fusion.

Authors:  Khaled A Alsaadi; Manar Alwohaib; Karen Pinto; Rola H Ali
Journal:  BMJ Case Rep       Date:  2022-02-19
  4 in total

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