Brian Chon1, Mary Qiu, Shan C Lin. 1. Department of Ophthalmology, University of California, San Francisco, San Francisco, California.
Abstract
PURPOSE: To examine the association between myopia and glaucoma, visual field defects, optic disc structural damage, and IOP in a population with a high prevalence of normal-tension glaucoma (NTG). METHODS: Data were included from 13,433 participants in the 2008 to 2011 Korean National Health and Nutrition Examination Survey, a cross-sectional study. Spherical equivalent was used to define refractive status as emmetropia (-0.99 to 0.99 diopters [D]), mild myopia (-1.00 to -2.99 D), moderate myopia (-3.00 to -5.99 D), severe myopia (<-6 D), and hyperopia (≥+1.00D). Glaucoma was defined by International Society for Geographical and Epidemiological Ophthalmology (ISGEO) criteria. RESULTS: Compared with those with emmetropia, the odds of a glaucoma diagnosis were higher with moderate myopia (odds ratio [OR] 2.2, 95% confidence interval [CI] 1.2-4.1) and severe myopia (OR 4.6, CI 2.3-9.4). Visual field defects were increased for mild myopia (OR 2.3, CI 1.2-4.5) and severe myopia (OR 20.9, CI 6.3-68.6). Optic disc structural damage was increased for moderate myopia (OR 1.8, CI 1.2-2.5) and severe myopia (OR 2.3, CI 1.5-3.7). Mean IOP was higher for mild myopia (14.4 mm Hg, CI 14.2-14.5 mm Hg), moderate myopia (14.7 mm Hg, CI 14.4-15.0 mm Hg), and severe myopia (14.7 mm Hg, CI 14.3-15.2 mmHg) compared with those with emmetropia (14.0 mm Hg, CI 13.9-14.1 mm Hg). CONCLUSIONS: In South Koreans, more severe myopia was associated with greater odds of glaucoma as defined by ISGEO criteria.
PURPOSE: To examine the association between myopia and glaucoma, visual field defects, optic disc structural damage, and IOP in a population with a high prevalence of normal-tension glaucoma (NTG). METHODS: Data were included from 13,433 participants in the 2008 to 2011 Korean National Health and Nutrition Examination Survey, a cross-sectional study. Spherical equivalent was used to define refractive status as emmetropia (-0.99 to 0.99 diopters [D]), mild myopia (-1.00 to -2.99 D), moderate myopia (-3.00 to -5.99 D), severe myopia (<-6 D), and hyperopia (≥+1.00D). Glaucoma was defined by International Society for Geographical and Epidemiological Ophthalmology (ISGEO) criteria. RESULTS: Compared with those with emmetropia, the odds of a glaucoma diagnosis were higher with moderate myopia (odds ratio [OR] 2.2, 95% confidence interval [CI] 1.2-4.1) and severe myopia (OR 4.6, CI 2.3-9.4). Visual field defects were increased for mild myopia (OR 2.3, CI 1.2-4.5) and severe myopia (OR 20.9, CI 6.3-68.6). Optic disc structural damage was increased for moderate myopia (OR 1.8, CI 1.2-2.5) and severe myopia (OR 2.3, CI 1.5-3.7). Mean IOP was higher for mild myopia (14.4 mm Hg, CI 14.2-14.5 mm Hg), moderate myopia (14.7 mm Hg, CI 14.4-15.0 mm Hg), and severe myopia (14.7 mm Hg, CI 14.3-15.2 mmHg) compared with those with emmetropia (14.0 mm Hg, CI 13.9-14.1 mm Hg). CONCLUSIONS: In South Koreans, more severe myopia was associated with greater odds of glaucoma as defined by ISGEO criteria.
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Authors: Kyung Chul Yoon; Won Choi; Hyo Seok Lee; Sang-Duck Kim; Seung-Hyun Kim; Chan Yun Kim; Ki Ho Park; Young Jeung Park; Seung-Hee Baek; Su Jeong Song; Jae Pil Shin; Suk-Woo Yang; Seung-Young Yu; Jong Soo Lee; Key Hwan Lim; Kyung Won Oh; Se Woong Kang Journal: Korean J Ophthalmol Date: 2015-11-25