| Literature DB >> 24019040 |
Olivier Berger1, Jean-Luc Montchamp.
Abstract
A great leap forward toward the general synthesis of P-stereogenic compounds: Heating H3 PO2 with (-)-menthol and paraformaldehyde gives easily crystallized menthyl hydroxymethyl-H-phosphinate (1). From this product, virtually any P-stereogenic compound can be synthesized.Entities:
Keywords: H-phosphinates; chiral auxiliaries; menthol; organophosphorus compounds; phosphinates
Year: 2013 PMID： 24019040 DOI： 10.1002/anie.201306628
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336