| Literature DB >> 24018470 |
Katherine A Lyseng-Williamson1, Sean T Duggan, Gillian M Keating.
Abstract
Pegylated liposomal doxorubicin (Caelyx(®) [EU], Doxil(®) [USA]) represents an improved formulation of conventional doxorubicin, with reduced cardiotoxicity and an improved pharmacokinetic profile. As shown by evidence from clinical trials, intravenous pegylated liposomal doxorubicin is a useful option in the treatment of various malignancies, including metastatic breast cancer, ovarian cancer, multiple myeloma, and AIDS-related Kaposi sarcoma. It has a favourable safety profile relative to conventional doxorubicin and other available chemotherapy agents.Entities:
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Year: 2013 PMID: 24018470 DOI: 10.1007/s40259-013-0070-1
Source DB: PubMed Journal: BioDrugs ISSN: 1173-8804 Impact factor: 5.807