Literature DB >> 24015763

Cu(2+)-responsive bimodal (optical/MRI) contrast agent for cellular imaging.

Joo Hee Jang1, Sankarprasad Bhuniya, Jongeun Kang, Areum Yeom, Kwan Soo Hong, Jong Seung Kim.   

Abstract

A water-soluble T1 magnetic resonance imaging contrast agent (1) has been synthesized. The bimodal contrast agent 1 responds to the Cu(2+) ion in living cells by enhancing the MRI modality signal whereas the optical signal gradually drops. This dual modality probe response depends on the cellular free copper ions in RAW 264.7 cells even at the micromolar level.

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Year:  2013        PMID： 24015763     DOI： 10.1021/ol4025293

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  8 in total

1.  Redox-responsive branched-bottlebrush polymers for in vivo MRI and fluorescence imaging.

Authors:  Molly A Sowers; Jessica R McCombs; Ying Wang; Joseph T Paletta; Stephen W Morton; Erik C Dreaden; Michael D Boska; M Francesca Ottaviani; Paula T Hammond; Andrzej Rajca; Jeremiah A Johnson
Journal:  Nat Commun       Date:  2014-11-18       Impact factor: 14.919

Review 2.  A review of responsive MRI contrast agents: 2005-2014.

Authors:  Dina V Hingorani; Adam S Bernstein; Mark D Pagel
Journal:  Contrast Media Mol Imaging       Date:  2014-10-29       Impact factor: 3.161

Review 3.  Recent development of contrast agents for magnetic resonance and multimodal imaging of glioblastoma.

Authors:  Danping Zhuang; Huifen Zhang; Genwen Hu; Bing Guo
Journal:  J Nanobiotechnology       Date:  2022-06-16       Impact factor: 9.429

4.  A Dual-Target Fluorescent Probe with Response-Time Dependent Selectivity for Cd2+ and Cu2.

Authors:  Zhengyu Zhang; Shizhuang Yuan; Enju Wang
Journal:  J Fluoresc       Date:  2018-08-06       Impact factor: 2.217

5.  Multimeric Near IR-MR Contrast Agent for Multimodal In Vivo Imaging.

Authors:  Victoria S R Harrison; Christiane E Carney; Keith W MacRenaris; Emily A Waters; Thomas J Meade
Journal:  J Am Chem Soc       Date:  2015-07-14       Impact factor: 15.419

6.  An Activatable T1-Weighted MR Contrast Agent: A Noninvasive Tool for Tracking the Vicinal Thiol Motif of Thioredoxin in Live Cells.

Authors:  Jongeun Kang; Eunha Hwang; Hyunseung Lee; Mi Young Cho; Sanu Karan; Hak Nam Kim; Jong Seung Kim; Jonathan L Sessler; Sankarprasad Bhuniya; Kwan Soo Hong
Journal:  Molecules       Date:  2021-04-01       Impact factor: 4.411

7.  A fluorescent and colorimetric probe based on naphthalene diimide and its high sensitivity towards copper ions when used as test strips.

Authors:  Luyi Zong; Can Wang; Yuchen Song; Jie Hu; Qianqian Li; Zhen Li
Journal:  RSC Adv       Date:  2019-04-24       Impact factor: 4.036

8.  Targeting Glioma with a Dual Mode Optical and Paramagnetic Nanoprobe across the Blood-brain Tumor Barrier.

Authors:  Kishor Karki; James R Ewing; Meser M Ali
Journal:  J Nanomed Nanotechnol       Date:  2016-08-31
  8 in total

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