| Literature DB >> 24014886 |
Shigeo Masuda1, Jun Wu, Tomoaki Hishida, Ganesh N Pandian, Hiroshi Sugiyama, Juan Carlos Izpisua Belmonte.
Abstract
Induced pluripotent stem cells (iPSCs) could be generated by a single gene Oct4 and chemical compounds, in which exogenous expression of Oct4 was indispensable for reprogramming. Recent advances in chemical-mediated cellular reprogramming suggest that small molecules alone (i.e. without Yamanaka factors) can successfully establish iPSCs from mouse somatic cells.Entities:
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Year: 2013 PMID: 24014886 DOI: 10.1093/jmcb/mjt034
Source DB: PubMed Journal: J Mol Cell Biol ISSN: 1759-4685 Impact factor: 6.216