Literature DB >> 24013811

Clinical nanomedicine: a solution to the chemotherapy conundrum in pediatric leukemia therapy.

V Krishnan1, A K Rajasekaran2.   

Abstract

Although chemotherapy-based treatment of leukemia has tremendously improved survival rates in children, induction of treatment-related side effects is a major concern in clinical oncology. The development of nanotechnology-based drug delivery techniques to target clinically approved anticancer agents specifically to leukemic cells should diminish toxic side effects. This review aims to address the rational design of nanotherapeutics in treating hematologic malignancies with a focus on acute lymphoblastic leukemia (ALL)--the most prominent form of pediatric cancer.

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Year:  2013        PMID： 24013811     DOI： 10.1038/clpt.2013.174

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN： 0009-9236            Impact factor:   6.875


  13 in total

1.  Click Nucleic Acid Mediated Loading of Prodrug Activating Enzymes in PEG-PLGA Nanoparticles for Combination Chemotherapy.

Authors:  Albert Harguindey; Shambojit Roy; Alexander W Harris; Benjamin D Fairbanks; Andrew P Goodwin; Christopher N Bowman; Jennifer N Cha
Journal:  Biomacromolecules       Date:  2019-03-26       Impact factor: 6.988

Review 2.  Current Advances in Black Phosphorus-Based Drug Delivery Systems for Cancer Therapy.

Authors:  Wenxin Liu; Alideertu Dong; Bing Wang; Han Zhang
Journal:  Adv Sci (Weinh)       Date:  2021-01-15       Impact factor: 16.806

3.  CD19-Targeted Nanodelivery of Doxorubicin Enhances Therapeutic Efficacy in B-Cell Acute Lymphoblastic Leukemia.

Authors:  Vinu Krishnan; Xian Xu; Dakota Kelly; Adam Snook; Scott A Waldman; Robert W Mason; Xinqiao Jia; Ayyappan K Rajasekaran
Journal:  Mol Pharm       Date:  2015-05-04       Impact factor: 4.939

4.  FPOA induces the apoptosis of HepG2 cells.

Authors:  Mingjie Song; Haiying Bao; Tolgor Bau
Journal:  Exp Ther Med       Date:  2018-01-08       Impact factor: 2.447

5.  Targeted therapy with MXD3 siRNA, anti-CD22 antibody and nanoparticles for precursor B-cell acute lymphoblastic leukaemia.

Authors:  Noriko Satake; Connie Duong; Cathy Chen; Gustavo A Barisone; Elva Diaz; Joseph Tuscano; David M Rocke; Jan Nolta; Nitin Nitin
Journal:  Br J Haematol       Date:  2014-09-08       Impact factor: 6.998

6.  Thermo-Sensitive Liposome co-Loaded of Vincristine and Doxorubicin Based on Their Similar Physicochemical Properties had Synergism on Tumor Treatment.

Authors:  Mingyuan Li; Zhiping Li; Yang Yang; Zhiyuan Wang; Zhenbo Yang; Bingsheng Li; Xiangyang Xie; Jinwen Song; Hui Zhang; Ying Li; Guangyu Gao; Jingyuan Yang; Xingguo Mei; Wei Gong
Journal:  Pharm Res       Date:  2016-04-13       Impact factor: 4.200

7.  A DOX-loaded polymer micelle for effectively inhibiting cancer cells.

Authors:  Huayang Feng; Dandan Chu; Zhanrong Li; Zhihua Guo; Lin Jin; Bingbing Fan; Junjie Zhang; Jingguo Li
Journal:  RSC Adv       Date:  2018-07-19       Impact factor: 4.036

Review 8.  Targeted delivery system of nanobiomaterials in anticancer therapy: from cells to clinics.

Authors:  Su-Eon Jin; Hyo-Eon Jin; Soon-Sun Hong
Journal:  Biomed Res Int       Date:  2014-02-19       Impact factor: 3.411

Review 9.  Targeted nanoparticles for pediatric leukemia therapy.

Authors:  Riyaz Basha; Nirupama Sabnis; Kenneth Heym; W Paul Bowman; Andras G Lacko
Journal:  Front Oncol       Date:  2014-05-13       Impact factor: 6.244

10.  Physiologically Based Pharmacokinetic Modeling of Fluorescently Labeled Block Copolymer Nanoparticles for Controlled Drug Delivery in Leukemia Therapy.

Authors:  M J Gilkey; V Krishnan; L Scheetz; X Jia; A K Rajasekaran; P S Dhurjati
Journal:  CPT Pharmacometrics Syst Pharmacol       Date:  2015-03-12
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