Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Interleukin-21, a potential diagnostic and therapeutic target for systemic lupus erythematosus.

Literature DB >> 24013715

Interleukin-21, a potential diagnostic and therapeutic target for systemic lupus erythematosus.

Yong He¹, Cheng Huang, Lei Zhang, Xiong-Wen Lv, Jun Li.

Abstract

Entities: Disease Gene

Mesh：

Substances：
Interleukins

Year: 2013 PMID： 24013715 DOI： 10.1007/s00296-013-2860-7

Source DB: PubMed Journal: Rheumatol Int ISSN： 0172-8172 Impact factor: 2.631

× No keyword cloud information.

14 in total

1. IL-21 promotes lupus-like disease in chronic graft-versus-host disease through both CD4 T cell- and B cell-intrinsic mechanisms.

Authors: Vinh Nguyen; Irina Luzina; Horea Rus; Cosmin Tegla; Ching Chen; Violeta Rus
Journal: J Immunol Date: 2012-06-20 Impact factor: 5.422

2. Copy number variations of interleukin-17F, interleukin-21, and interleukin-22 are associated with systemic lupus erythematosus.

Authors: Bo Yu; Ming Guan; Yinghui Peng; Yong Shao; Chao Zhang; Xupeng Yue; Jie Zhang; Hong Yang; Hejian Zou; Wencai Ye; Jun Wan; Wei Zhang
Journal: Arthritis Rheum Date: 2011-11

3. IL-21 receptor is required for the systemic accumulation of activated B and T lymphocytes in MRL/MpJ-Fas(lpr/lpr)/J mice.

Authors: Andrew L Rankin; Heath Guay; Deborah Herber; Sarah A Bertino; Tatyana A Duzanski; Yijun Carrier; Sean Keegan; Mayra Senices; Nancy Stedman; Mark Ryan; Laird Bloom; Quintus Medley; Mary Collins; Cheryl Nickerson-Nutter; Joe Craft; Deborah Young; Kyri Dunussi-Joannopoulos
Journal: J Immunol Date: 2012-01-09 Impact factor: 5.422

Review 4. Interleukin-21 as a potential therapeutic target for systemic lupus erythematosus.

Authors: Jing Li; Hai-Feng Pan; Han Cen; Jing Tian; Yan Ma; Jin-Hui Tao; Dong-Qing Ye
Journal: Mol Biol Rep Date: 2010-11-24 Impact factor: 2.316

5. IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression.

Authors: Deborah Herber; Thomas P Brown; Spencer Liang; Deborah A Young; Mary Collins; Kyri Dunussi-Joannopoulos
Journal: J Immunol Date: 2007-03-15 Impact factor: 5.422

6. A single nucleotide polymorphism of IL-21 gene is associated with systemic lupus erythematosus in a Chinese population.

Authors: Lei Ding; Song Wang; Gui-Mei Chen; Rui-Xue Leng; Hai-Feng Pan; Dong-Qing Ye
Journal: Inflammation Date: 2012-12 Impact factor: 4.092

1. Genetic characterization of interleukins (IL-1α, IL-1β, IL-2, IL-4, IL-8, IL-10, IL-12A, IL-12B, IL-15 and IL-18) with relevant biological roles in lagomorphs.

Authors: Fabiana Neves; Joana Abrantes; Tereza Almeida; Ana Lemos de Matos; Paulo P Costa; Pedro J Esteves
Journal: Innate Immun Date: 2015-09-21 Impact factor: 2.680

1 in total

Interleukin-21, a potential diagnostic and therapeutic target for systemic lupus erythematosus.

1. IL-21 promotes lupus-like disease in chronic graft-versus-host disease through both CD4 T cell- and B cell-intrinsic mechanisms.

2. Copy number variations of interleukin-17F, interleukin-21, and interleukin-22 are associated with systemic lupus erythematosus.

3. IL-21 receptor is required for the systemic accumulation of activated B and T lymphocytes in MRL/MpJ-Fas(lpr/lpr)/J mice.

Review 4. Interleukin-21 as a potential therapeutic target for systemic lupus erythematosus.

5. IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression.

6. A single nucleotide polymorphism of IL-21 gene is associated with systemic lupus erythematosus in a Chinese population.

7. Elevated production of B cell chemokine CXCL13 is correlated with systemic lupus erythematosus disease activity.

8. Decreased serum level of IL-21 in new-onset systemic lupus erythematosus patients.

9. Interleukin 21 correlates with T cell and B cell subset alterations in systemic lupus erythematosus.

10. Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus.

1. Genetic characterization of interleukins (IL-1α, IL-1β, IL-2, IL-4, IL-8, IL-10, IL-12A, IL-12B, IL-15 and IL-18) with relevant biological roles in lagomorphs.