| Literature DB >> 24012401 |
Karen A Cadoo1, Tiffany A Traina, Tari A King.
Abstract
The identification of the intrinsic molecular subtypes of breast cancer has enhanced our understanding of tumor biology, informing therapeutic targets, and clinical trial design. This article reviews the intrinsic classification system and the clinically defined subtypes of breast cancer. We review the molecular drivers of each subtype and discuss implications for prognosis, clinical management, and future directions.Entities:
Keywords: Breast cancer; Endocrine therapy; HER2 positive; Intrinsic subtypes; Resistance; Triple negative
Mesh:
Year: 2013 PMID: 24012401 DOI: 10.1016/j.soc.2013.06.006
Source DB: PubMed Journal: Surg Oncol Clin N Am ISSN: 1055-3207 Impact factor: 3.495