Literature DB >> 24011068

Mrap2: an accessory protein linked to obesity.

Tiemin Liu1, Joel K Elmquist, Kevin W Williams.   

Abstract

Melanocortin receptors are critical modulators of energy balance and glucose homeostasis. Companion studies published in Science (Asai et al., 2013; Sebag et al., 2013) establish a role for melanocortin receptor accessory protein 2 (Mrap2) in regulating melanocortin receptor activity and in the development of obesity in zebrafish, rodents, and humans.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID： 24011068      PMCID： PMC3930449          DOI： 10.1016/j.cmet.2013.08.016

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  10 in total

Review 1.  Studies on the physiological functions of the melanocortin system.

Authors:  Roger D Cone
Journal:  Endocr Rev       Date:  2006-10-31       Impact factor: 19.871

Review 2.  Targeting melanocortin receptors: an approach to treat weight disorders and sexual dysfunction.

Authors:  Jarl E S Wikberg; Felikss Mutulis
Journal:  Nat Rev Drug Discov       Date:  2008-04       Impact factor: 84.694

3.  Role of the central melanocortin system in cachexia.

Authors:  D L Marks; N Ling; R D Cone
Journal:  Cancer Res       Date:  2001-02-15       Impact factor: 12.701

4.  Profound obesity associated with a balanced translocation that disrupts the SIM1 gene.

Authors:  J L Holder; N F Butte; A R Zinn
Journal:  Hum Mol Genet       Date:  2000-01-01       Impact factor: 6.150

5.  Divergence of melanocortin pathways in the control of food intake and energy expenditure.

Authors:  Nina Balthasar; Louise T Dalgaard; Charlotte E Lee; Jia Yu; Hisayuki Funahashi; Todd Williams; Manuel Ferreira; Vinsee Tang; Robert A McGovern; Christopher D Kenny; Lauryn M Christiansen; Elizabeth Edelstein; Brian Choi; Olivier Boss; Carl Aschkenasi; Chen-yu Zhang; Kathleen Mountjoy; Toshiro Kishi; Joel K Elmquist; Bradford B Lowell
Journal:  Cell       Date:  2005-11-04       Impact factor: 41.582

6.  Melanocortin 4 receptors reciprocally regulate sympathetic and parasympathetic preganglionic neurons.

Authors:  Jong-Woo Sohn; Louise E Harris; Eric D Berglund; Tiemin Liu; Linh Vong; Bradford B Lowell; Nina Balthasar; Kevin W Williams; Joel K Elmquist
Journal:  Cell       Date:  2013-01-31       Impact factor: 41.582

7.  Developmental control of the melanocortin-4 receptor by MRAP2 proteins in zebrafish.

Authors:  Julien A Sebag; Chao Zhang; Patricia M Hinkle; Amanda M Bradshaw; Roger D Cone
Journal:  Science       Date:  2013-07-19       Impact factor: 47.728

8.  Modulation of blood pressure by central melanocortinergic pathways.

Authors:  Jerry R Greenfield; Jeffrey W Miller; Julia M Keogh; Elana Henning; Julie H Satterwhite; Gregory S Cameron; Beatrice Astruc; John P Mayer; Soren Brage; Teik Choon See; David J Lomas; Stephen O'Rahilly; I Sadaf Farooqi
Journal:  N Engl J Med       Date:  2008-12-17       Impact factor: 91.245

9.  Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity.

Authors:  Masato Asai; Shwetha Ramachandrappa; Maria Joachim; Yuan Shen; Rong Zhang; Nikhil Nuthalapati; Visali Ramanathan; David E Strochlic; Peter Ferket; Kirsten Linhart; Caroline Ho; Tatiana V Novoselova; Sumedha Garg; Martin Ridderstråle; Claude Marcus; Joel N Hirschhorn; Julia M Keogh; Stephen O'Rahilly; Li F Chan; Adrian J Clark; I Sadaf Farooqi; Joseph A Majzoub
Journal:  Science       Date:  2013-07-19       Impact factor: 47.728

10.  The melanocortin receptors and their accessory proteins.

Authors:  Shwetha Ramachandrappa; Rebecca J Gorrigan; Adrian J L Clark; Li F Chan
Journal:  Front Endocrinol (Lausanne)       Date:  2013-02-08       Impact factor: 5.555
  10 in total
  8 in total

Review 1.  Melanocortin neurons: Multiple routes to regulation of metabolism.

Authors:  Wen-Jie Shen; Ting Yao; Xingxing Kong; Kevin W Williams; Tiemin Liu
Journal:  Biochim Biophys Acta Mol Basis Dis       Date:  2017-05-09       Impact factor: 5.187

Review 2.  Molecular and cellular regulation of hypothalamic melanocortin neurons controlling food intake and energy metabolism.

Authors:  M Koch; T L Horvath
Journal:  Mol Psychiatry       Date:  2014-04-15       Impact factor: 15.992

3.  Genetic differentiation in East African ethnicities and its relationship with endurance running success.

Authors:  André L S Zani; Mateus H Gouveia; Marla M Aquino; Rodrigo Quevedo; Rodrigo L Menezes; Charles Rotimi; Gerald O Lwande; Collins Ouma; Ephrem Mekonnen; Nelson J R Fagundes
Journal:  PLoS One       Date:  2022-05-19       Impact factor: 3.752

4.  A 6q14.1-q15 microdeletion in a male patient with severe autistic disorder, lack of oral language, and dysmorphic features with concomitant presence of a maternally inherited Xp22.31 copy number gain.

Authors:  Ines Quintela; Montse Fernandez-Prieto; Lorena Gomez-Guerrero; Mariela Resches; Jesus Eiris; Francisco Barros; Angel Carracedo
Journal:  Clin Case Rep       Date:  2015-04-09

5.  Pharmacological modulation of MRAP2 protein on melanocortin receptors in the sea lamprey.

Authors:  Ming Zhu; Bingxin Xu; Meng Wang; Shangyun Liu; Yue Zhang; Chao Zhang
Journal:  Endocr Connect       Date:  2019-04       Impact factor: 3.335

Review 6.  The lymphatic vascular system: much more than just a sewer.

Authors:  Jörg Wilting; Jürgen Becker
Journal:  Cell Biosci       Date:  2022-09-15       Impact factor: 9.584

Review 7.  Imprinting genes associated with endometriosis.

Authors:  Hiroshi Kobayashi
Journal:  EXCLI J       Date:  2014-03-13       Impact factor: 4.068

8.  Overexpression of melanocortin 2 receptor accessory protein 2 (MRAP2) in adult paraventricular MC4R neurons regulates energy intake and expenditure.

Authors:  Giuseppe Bruschetta; Jung Dae Kim; Sabrina Diano; Li F Chan
Journal:  Mol Metab       Date:  2018-10-04       Impact factor: 7.422
  8 in total

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