UNLABELLED: Background : Cardiovascular mortality and morbidity are high in chronic renal failure (CRF) patients. Increased dispersion of QT intervals is known to predispose to ventricular arrhythmias and sudden cardiac death. This study was conducted to assess the effect of hemodialysis (HD) on corrected QT (QTc) intervals and their dispersions (QTd) in chronic hemodialyzed patients. METHODS: Fifty-eight patients ( mean age 54.2±15.8 years) with chronic renal disease on chronic hemodialysis (HD) were assessed by standard examination including blood pressure, body weight, heart rate, 12-lead electrocardiography and laboratory tests like electrolytes (Na (+), K (+), Ca (++), phosphate), urea, and creatinine 30 minutes before and after HD. The QT intervals and QTc QTc= QT √R-R/ (in milli seconds [ms]) for each lead were measured manually by one observer using calipers. The difference between the maximum and the minimum of QT interval was noted as QT dispersion (QT d). RESULTS: The mean of pre and post dialysis R-R intervals was 859.22±96.85 ms and 870.43±91.45 ms, respectively (p>0.05). The mean of corrected QT cmax intervals increased significantly from 423.45±24.10 to 454.41±30.25 ms (p<0.05). The mean of QT dispersions and the corrected QT interval dispersions changed from 51.56±12.45 to 63.21±14.43 ms (p<0.05) from 59.40±13.58 to 68.33±14.55 ms (p<0.05), respectively. The changes in serum potassium and calcium levels were related with QT interval prolongation. CONCLUSION: QT and QTc interval and dispersion increase in HD patients. Prolonged QT interval indices had relation with K(+) and Ca(++) ions before but not after HD.
UNLABELLED: Background : Cardiovascular mortality and morbidity are high in chronic renal failure (CRF) patients. Increased dispersion of QT intervals is known to predispose to ventricular arrhythmias and sudden cardiac death. This study was conducted to assess the effect of hemodialysis (HD) on corrected QT (QTc) intervals and their dispersions (QTd) in chronic hemodialyzed patients. METHODS: Fifty-eight patients ( mean age 54.2±15.8 years) with chronic renal disease on chronic hemodialysis (HD) were assessed by standard examination including blood pressure, body weight, heart rate, 12-lead electrocardiography and laboratory tests like electrolytes (Na (+), K (+), Ca (++), phosphate), urea, and creatinine 30 minutes before and after HD. The QT intervals and QTc QTc= QT √R-R/ (in milli seconds [ms]) for each lead were measured manually by one observer using calipers. The difference between the maximum and the minimum of QT interval was noted as QT dispersion (QT d). RESULTS: The mean of pre and post dialysis R-R intervals was 859.22±96.85 ms and 870.43±91.45 ms, respectively (p>0.05). The mean of corrected QT cmax intervals increased significantly from 423.45±24.10 to 454.41±30.25 ms (p<0.05). The mean of QT dispersions and the corrected QT interval dispersions changed from 51.56±12.45 to 63.21±14.43 ms (p<0.05) from 59.40±13.58 to 68.33±14.55 ms (p<0.05), respectively. The changes in serum potassium and calcium levels were related with QT interval prolongation. CONCLUSION: QT and QTc interval and dispersion increase in HDpatients. Prolonged QT interval indices had relation with K(+) and Ca(++) ions before but not after HD.
Authors: Abdenasser Drighil; John E Madias; Hanane El Mosalami; Nadia El Badaoui; Ahmed Bennis; Bahija Mouine; Wafae Fadili; Beenyouness Ramdani Journal: Ann Noninvasive Electrocardiol Date: 2007-04 Impact factor: 1.468
Authors: Adrian Covic; Mirela Diaconita; Paul Gusbeth-Tatomir; Maria Covic; Adrian Botezan; Gabriel Ungureanu; David J Goldsmith Journal: Nephrol Dial Transplant Date: 2002-12 Impact factor: 5.992
Authors: Allan D Sniderman; Amirreza Solhpour; Ahsan Alam; Ken Williams; James A Sloand Journal: Clin J Am Soc Nephrol Date: 2010-01-07 Impact factor: 8.237
Authors: José Luis Cobo Sánchez; Ana Rosa Alconero Camarero; María Casaus Pérez; Ma Angeles Maza Sota; Camino Villa Llamazares; Carmen Hiquera Roldán; Raquel Menezo Viadero; Rosa Alonso Nates Journal: J Ren Care Date: 2007 Jul-Sep
Authors: Carolina Salcedo; Pieter H Joubert; Miguel D Ferrer; Ana Z Canals; Francisco Maduell; Vicens Torregrosa; Josep Maria Campistol; Raquel Ojeda; Joan Perelló Journal: Br J Clin Pharmacol Date: 2019-02-19 Impact factor: 4.335
Authors: Hassaan A Bukhari; Carlos Sánchez; José Esteban Ruiz; Mark Potse; Pablo Laguna; Esther Pueyo Journal: Sensors (Basel) Date: 2022-04-12 Impact factor: 3.847
Authors: Jonah M Graves; Julian A Vallejo; Chelsea S Hamill; Derek Wang; Rohan Ahuja; Shaan Patel; Christian Faul; Michael J Wacker Journal: Am J Physiol Heart Circ Physiol Date: 2021-04-30 Impact factor: 5.125
Authors: Jacqueline Watt; Jessica Fitzpatrick; Stephen M Sozio; Bernard G Jaar; Michelle M Estrella; Larisa G Tereshchenko; Jose M Monroy-Trujillo; Michael Walsh; Rulan S Parekh Journal: BMC Nephrol Date: 2022-01-27 Impact factor: 2.388
Authors: José Alberto Navarro-García; Rafael Salguero-Bodes; Laura González-Lafuente; Laura Martín-Nunes; Elena Rodríguez-Sánchez; Teresa Bada-Bosch; Eduardo Hernández; Evangelina Mérida-Herrero; Manuel Praga; Jorge Solís; Fernando Arribas; Héctor Bueno; Makoto Kuro-O; María Fernández-Velasco; Luis Miguel Ruilope; Carmen Delgado; Gema Ruiz-Hurtado Journal: BMC Med Date: 2022-01-19 Impact factor: 8.775