| Literature DB >> 24009103 |
Friedrich Freiberger1, Raphael Böhm, David Schwarzer, Rita Gerardy-Schahn, Thomas Haselhorst, Mark von Itzstein.
Abstract
Highly disciplined transfers: Polysialyltransferases are important enzymes responsible for the biosynthesis of α-linked polysialic acids. We used a multidisciplinary approach, and propose the first substrate-binding model for a bacterial polysialyltransferase. Furthermore, we identify key amino acid residues involved in catalysis.Entities:
Keywords: NMR spectroscopy; enzyme models; glycosyltransferases; polysialic acids; sialic acids
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Year: 2013 PMID： 24009103 DOI： 10.1002/cbic.201300367
Source DB: PubMed Journal: Chembiochem ISSN： 1439-4227 Impact factor: 3.164