Literature DB >> 24008099

Enhanced glucagon-like peptide-1 secretion in a patient with glucagonoma: implications for glucagon-like peptide-1 secretion from pancreatic α cells in vivo.

Daisuke Yabe1, Mariyo Rokutan, Yoshiyuki Miura, Izumi Komoto, Ryota Usui, Hitoshi Kuwata, Koin Watanabe, Takanori Hyo, Takeshi Kurose, Terumi Nagamatsu, Shinobu Shimizu, Jun Kawai, Masayuki Imamura, Yutaka Seino.   

Abstract

We examined GLP-1 secretion from the pancreas of a patient with glucagonoma and pancreatic resection by measuring GLP-1 after meal ingestion or selective arterial calcium injection, and immunohistochemical analysis. Our findings support the notion that GLP-1 is secreted from pancreatic α cells in humans.
Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  GIP; GLP-1; Glucagon-like peptide-1; Glucagonoma; MEN1; Pancreatic α cells; glucagon-like peptide 1; glucose-dependent insulinotropic polypepide; multiple endocrine neoplasia syndrome, type 1

Mesh：

Substances：

Year:  2013        PMID： 24008099     DOI： 10.1016/j.diabres.2013.08.005

Source DB:  PubMed          Journal:  Diabetes Res Clin Pract        ISSN： 0168-8227            Impact factor:   5.602


  5 in total

1.  Betacellulin-Induced α-Cell Proliferation Is Mediated by ErbB3 and ErbB4, and May Contribute to β-Cell Regeneration.

Authors:  Young-Sun Lee; Gyun Jee Song; Hee-Sook Jun
Journal:  Front Cell Dev Biol       Date:  2021-01-21

2.  Administration of Jerusalem artichoke reduces the postprandial plasma glucose and glucose-dependent insulinotropic polypeptide (GIP) concentrations in humans.

Authors:  Hirokazu Takahashi; Akane Nakajima; Yuichi Matsumoto; Hitoe Mori; Kanako Inoue; Hiroko Yamanouchi; Kenichi Tanaka; Yuki Tomiga; Maki Miyahara; Tomomi Yada; Yumiko Iba; Yayoi Matsuda; Keiichi Watanabe; Keizo Anzai
Journal:  Food Nutr Res       Date:  2022-04-04       Impact factor: 3.894

Review 3.  Action and therapeutic potential of oxyntomodulin.

Authors:  Alessandro Pocai
Journal:  Mol Metab       Date:  2013-12-14       Impact factor: 7.422

4.  Meal sequence and glucose excursion, gastric emptying and incretin secretion in type 2 diabetes: a randomised, controlled crossover, exploratory trial.

Authors:  Hitoshi Kuwata; Masahiro Iwasaki; Shinobu Shimizu; Kohtaro Minami; Haruyo Maeda; Susumu Seino; Koji Nakada; Chihiro Nosaka; Kenta Murotani; Takeshi Kurose; Yutaka Seino; Daisuke Yabe
Journal:  Diabetologia       Date:  2015-12-24       Impact factor: 10.122

5.  Glucagon-Like Peptide-1 Receptor Agonist and Glucagon Increase Glucose-Stimulated Insulin Secretion in Beta Cells via Distinct Adenylyl Cyclases.

Authors:  Young-Sun Lee; Hee-Sook Jun
Journal:  Int J Med Sci       Date:  2018-03-14       Impact factor: 3.738
  5 in total

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