Literature DB >> 24005879

Etiological evaluation of patients presenting with isolated micropenis to an academic health care center.

Tugba Bilmez Aslan1, Fatih Gurbuz, Fatih Temiz, Bilgin Yuksel, Ali Kemal Topaloglu.   

Abstract

OBJECTIVE: To evaluate etiology of the patients with micropenis presenting to a tertiary health care center.
METHODS: In this prospective study all patients who were referred with a diagnosis of micropenis from October 2009 through October 2010, underwent a complete evaluation including measurement of stretched penile length.
RESULTS: In 20 (31 %) among a total of 65 patients, measured stretched penile length was not consistent with the description of micropenis. True presence of micropenis was confirmed in the remaining 45 of total 65 cases (69 %). Etiological cause was determined in 29 patients (44 %) with the most common cause being hypogonadotropic hypogonadism. No etiological cause could be found in 16 patients (25 %).
CONCLUSIONS: In approximately one third of patients the presence of micropenis was not confirmed. The most common causes of misdiagnosis were buried penis due to obesity, erroneous measurement of stretched penile length, and/or lack of knowledge on population standards for penile length. Etiological basis of micropenis is rather heterogeneous. Despite extensive investigations, no causal link was found in around one fourth of cases. Accurate measurement and utilization of internationally accepted standards is utmost important for diagnosis and management of micropenis.

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Year:  2013        PMID: 24005879     DOI: 10.1007/s12098-013-1205-6

Source DB:  PubMed          Journal:  Indian J Pediatr        ISSN: 0019-5456            Impact factor:   1.967


  7 in total

1.  The child with micropenis.

Authors:  P S Menon; U A Khatwa
Journal:  Indian J Pediatr       Date:  2000-06       Impact factor: 1.967

2.  Maternal progestin intake and risk of hypospadias.

Authors:  Suzan L Carmichael; Gary M Shaw; Cecile Laurent; Mary S Croughan; Richard S Olney; Edward J Lammer
Journal:  Arch Pediatr Adolesc Med       Date:  2005-10

Review 3.  When size matters: a clinical review of pathological micropenis.

Authors:  Shirley Tsang
Journal:  J Pediatr Health Care       Date:  2009-07-23       Impact factor: 1.812

4.  Environmental xenoestrogens, antiandrogens and disorders of male sexual differentiation.

Authors:  C Sultan; P Balaguer; B Terouanne; V Georget; F Paris; C Jeandel; S Lumbroso; J Nicolas
Journal:  Mol Cell Endocrinol       Date:  2001-06-10       Impact factor: 4.102

5.  Bilateral anorchia in infancy: occurence of micropenis and the effect of testosterone treatment.

Authors:  D Zenaty; F Dijoud; Y Morel; S Cabrol; P Mouriquand; M Nicolino; C Bouvatier; G Pinto; C Lecointre; C Pienkowski; S Soskin; M Bost; A M Bertrand; A El-Ghoneimi; C Nihoul-Fekete; J Léger
Journal:  J Pediatr       Date:  2006-11       Impact factor: 4.406

6.  Micropenis. I. Criteria, etiologies and classification.

Authors:  P A Lee; T Mazur; R Danish; J Amrhein; R M Blizzard; J Money; C J Migeon
Journal:  Johns Hopkins Med J       Date:  1980-04

7.  Distribution of gene mutations associated with familial normosmic idiopathic hypogonadotropic hypogonadism.

Authors:  Fatih Gürbüz; L Damla Kotan; Eda Mengen; Zeynep Şıklar; Merih Berberoğlu; Sebila Dökmetaş; Mehmet Fatih Kılıçlı; Ayla Güven; Birgül Kirel; Nurçin Saka; Şükran Poyrazoğlu; Yaşar Cesur; Murat Doğan; Samim Özen; Mehmet Nuri Özbek; Hüseyin Demirbilek; M Burcu Kekil; Fatih Temiz; Neslihan Önenli Mungan; Bilgin Yüksel; Ali Kemal Topaloğlu
Journal:  J Clin Res Pediatr Endocrinol       Date:  2012-07-05
  7 in total

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