| Literature DB >> 24004304 |
Jingyu Zhang1, Wael M Abdel-Mageed, Miaomiao Liu, Pei Huang, Wenni He, Li Li, Fuhang Song, Huanqin Dai, Xueting Liu, Jingyu Liang, Lixin Zhang.
Abstract
Serial antibacterial furanoditerpenes caesanines A-D (1-4), possessing a cassane-type diterpenoid skeleton with an unusual N bridge between C-19/C-20, were identified from a Chinese herb Caesalpinia sappan Linn. In addition, caesanine D (4) showed the first class of dicassane diterpenoid ethers. Their structures were determined by different spectroscopic methods and ECD calculation. Caesanines A and B exhibited strong activities against MRSA suggesting a promising entry point for the development of anti-infective drugs.Entities:
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Year: 2013 PMID： 24004304 DOI： 10.1021/ol402058z
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005