| Literature DB >> 24004188 |
Takahiro Shiba1, Takuya Kurahashi, Seijiro Matsubara.
Abstract
We have developed a nickel-catalyzed transformation, in which phthalimides react with trimethylsilyl-substituted alkynes in the presence of Ni(0)/PMe3/MAD catalyst to provide isoindolinones. The reaction process displays an unusual mechanistic feature-decarbonylation and alkylidenation. The use of both trimethylsilyl-substiuted alkynes and MAD was found to be essential for the transformation with high selectivities.Entities:
Year: 2013 PMID： 24004188 DOI： 10.1021/ja4068172
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419