| Literature DB >> 24002101 |
Elizabeth S Zhu1, George R Thompson, Christopher Kreulen, Eric Giza.
Abstract
Use of amphotericin B-impregnated bone cement in combination with systemic antifungals for the treatment of coccidioidal osteomyelitis offers the potential for sustained local concentrations of drug at the site of the infection. Amphotericin B levels in bone of up to 5.1 μg/g have been demonstrated 4 months after placement of bone cement.Entities:
Mesh:
Substances:
Year: 2013 PMID: 24002101 PMCID: PMC3837876 DOI: 10.1128/AAC.00963-13
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191