| Literature DB >> 24001714 |
Yi Zhang1, Lili Liu2, Jing Gao2, Chunhua Wu2, Lifeng Han2, Erwei Liu2, Pingping Shi2, Xiumei Gao3, Tao Wang3.
Abstract
Five new secoiridoids, nuzhenal C (1), 6'-O-trans-cinnamoyl iso-8-epikingisidic acid (2), ligulucidumosides A (3), B (4), and C (5), were obtained from the fruits of Ligustrum lucidum Ait. Their structures were elucidated by chemical and spectroscopic methods (UV, IR, HRESI-TOF-MS, 1D and 2D NMR). Among them, compound 3 is the first 1-OCH3 substituent secoiridoid obtained from plant kingdom. Furthermore, activity screening results showed that all of the isolates had triglyceride accumulation inhibitory effects in HepG2 cells.Entities:
Keywords: HepG2 cells; Ligustrum lucidum; Secoiridoids; Triglyceride accumulation inhibitory effects
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Year: 2013 PMID： 24001714 DOI： 10.1016/j.fitote.2013.08.022
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882