Literature DB >> 24001461

Study design, participation and characteristics of the Danish General Suburban Population Study.

Helle K M Bergholdt1, Lise Bathum, Jan Kvetny, Dorthe B Rasmussen, Birgitte Moldow, Tracy Hoeg, Gregor B E Jemec, Helle Berner-Nielsen, Børge G Nordestgaard, Christina Ellervik.   

Abstract

INTRODUCTION: The aim of this article was to describe the study design, participants and baseline characteristics of The Danish General Suburban Population Study (GESUS) and to compare suburban participants with age- and gender-matched urban participants from the Copenhagen General Population Study (CGPS).
MATERIAL AND METHODS: Data from questionnaire, health examination, biochemical measurements and public registers were collected.
RESULTS: In GESUS the overall participation rate was 49.3% (response n = 10,621 of total n = 21,557). Among people aged 40-79 years, the participation rate was 53.9% (8,797/16,310). Participants were more frequently women, had a higher median age, a higher frequency of marriage/registered partnerships, but had a lower frequency of co-morbidities and death in the follow-up period (January 2010-May 2011 (diseases)/June 2011 (death) than the non-participants. GESUS has sufficient power to study effects of rare and common exposures or genetic variants on the occurrence of common multifactorial diseases. Compared with an age- and gender-matched urban population (n = 10,618, CGPS), participants in GESUS (n = 10,618) were less physically active, smoked less and ingested less alcohol, had higher anthropometric measures, less undiagnosed hypertension but more undiagnosed diabetes, had a lower frequency of elevated total cholesterol and low-density lipoprotein chol-esterol but higher frequency of decreased high-density lipoprotein cholesterol and elevated triglycerides.
CONCLUSION: In GESUS, participants had a better health profile than non-participants, and participants in GESUS had a different cardiovascular risk profile than participants in the CGPS. FUNDING: The study received funding from the following: Johan and Lise Boserup Foundation; TrygFonden; Det Kommunale Momsfond; Johannes Fog's Foundation; Region Zealand; Region Zealand Foundation; Naestved Hospital; Naestved Hospital Foundation; The National Board of Health; Danish Agency for Science, Technology and Innovation. TRIAL REGISTRATION: not relevant.

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Year:  2013        PMID: 24001461

Source DB:  PubMed          Journal:  Dan Med J        ISSN: 2245-1919            Impact factor:   1.240


  14 in total

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Authors:  Anders Jorgensen; Kristin Köhler-Forsberg; Trine Henriksen; Allan Weimann; Ivan Brandslund; Christina Ellervik; Henrik E Poulsen; Gitte Moos Knudsen; Vibe G Frokjaer; Martin B Jorgensen
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4.  Impaired Fertility Associated with Subclinical Hypothyroidism and Thyroid Autoimmunity: The Danish General Suburban Population Study.

Authors:  Anne-Dorthe Feldthusen; Palle L Pedersen; Jacob Larsen; Tina Toft Kristensen; Christina Ellervik; Jan Kvetny
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5.  Weight Gain and Serum TSH Increase within the Reference Range after Hemithyroidectomy Indicate Lowered Thyroid Function.

Authors:  Tina Toft Kristensen; Jacob Larsen; Palle Lyngsie Pedersen; Anne-Dorthe Feldthusen; Christina Ellervik; Søren Jelstrup; Jan Kvetny
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6.  Social disparities in diabetes care: a general population study in Denmark.

Authors:  Andreas Heltberg; John Sahl Andersen; Jakob Kragstrup; Volkert Siersma; Håkon Sandholdt; Christina Ellervik
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Authors:  Anne-Dorthe Feldthusen; Jacob Larsen; Palle L Pedersen; Tina Toft Kristensen; Jan Kvetny
Journal:  J Clin Transl Endocrinol       Date:  2013-12-24

9.  Lactase Persistence, Milk Intake, and Adult Acne: A Mendelian Randomization Study of 20,416 Danish Adults.

Authors:  Christian R Juhl; Helle K M Bergholdt; Iben M Miller; Gregor B E Jemec; Jørgen K Kanters; Christina Ellervik
Journal:  Nutrients       Date:  2018-08-08       Impact factor: 5.717

10.  Socio-demographic determinants and effect of structured personal diabetes care: a 19-year follow-up of the randomized controlled study diabetes Care in General Practice (DCGP).

Authors:  Andreas Heltberg; Volkert Siersma; John Sahl Andersen; Christina Ellervik; Henrik Brønnum-Hansen; Jakob Kragstrup; Niels de Fine Olivarius
Journal:  BMC Endocr Disord       Date:  2017-12-08       Impact factor: 2.763

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