Literature DB >> 24001212

Applications of poly(ethylene oxide) in controlled release tablet systems: a review.

Lulu Ma1, Li Deng, Jianming Chen.   

Abstract

To improve therapeutic effects and compatibility of patients, controlled release tablet systems based on polymers are of great interest for pharmaceutical technologies. Poly(ethylene oxide) (PEO) is a non-ionic linear hydrophilic and uncrosslinked polymer available in a number of molecular weights. It is synthesized by ethylene oxide and has many desirable properties for drug delivery applications. This review article aims to summary the recent developments on physicochemical properties of PEO and focus on the recent efforts and developments on PEO as oral controlled release matrix tablets, bioadhesive hydrophilic matrices and osmotic pump tablets. Commercial products employed PEO were also discussed.

Entities:  

Keywords:  Bioadhesive hydrophilic matrix; PEO; commercial product; controlled release tablet; matrix tablet; osmotic pump tablet; physicochemical properties

Mesh：

Substances：

Year:  2013        PMID： 24001212     DOI： 10.3109/03639045.2013.831438

Source DB:  PubMed          Journal:  Drug Dev Ind Pharm        ISSN： 0363-9045            Impact factor:   3.225


  8 in total

1.  Formulation development, optimization, and evaluation of sustained release tablet of valacyclovir hydrochloride by combined approach of floating and swelling for better gastric retention.

Authors:  Pratik Upadhyay; Kunal Nayak; Kaushika Patel; Jaymin Patel; Shreeraj Shah; Jayant Deshpande
Journal:  Drug Deliv Transl Res       Date:  2014-12       Impact factor: 4.617

2.  Effect of Manufacturing Process on the Retention of Abuse-Deterrent Properties of PEO-Matrix Tablets.

Authors:  Leyla Rezaei; Saikishore Meruva; Maureen D Donovan
Journal:  AAPS PharmSciTech       Date:  2021-12-27       Impact factor: 3.246

3.  Extended release pellets prepared by hot melt extrusion technique for abuse deterrent potential: Category-1 in-vitro evaluation.

Authors:  Arun Butreddy; Sandeep Sarabu; Nagireddy Dumpa; Suresh Bandari; Michael A Repka
Journal:  Int J Pharm       Date:  2020-07-10       Impact factor: 5.875

4.  In Vitro Nasal Tissue Model for the Validation of Nasopharyngeal and Midturbinate Swabs for SARS-CoV-2 Testing.

Authors:  Devon R Hartigan; Miryam Adelfio; Molly E Shutt; Stephanie M Jones; Shreya Patel; Joshua T Marchand; Pamela D McGuinness; Bryan O Buchholz; Chiara E Ghezzi
Journal:  ACS Omega       Date:  2022-03-29

5.  Preparation, Properties and Water Dissolution Behavior of Polyethylene Oxide Mats Prepared by Solution Blow Spinning.

Authors:  Miguel Ángel Lorente; Gustavo González-Gaitano; Javier González-Benito
Journal:  Polymers (Basel)       Date:  2022-03-23       Impact factor: 4.329

6.  Formulation and Evaluation of Fenbendazole Extended-Release Extrudes Processed by Hot-Melt Extrusion.

Authors:  Gilberto S N Bezerra; Tielidy A de M de Lima; Declan M Colbert; Joseph Geever; Luke Geever
Journal:  Polymers (Basel)       Date:  2022-10-06       Impact factor: 4.967

7.  Development of a Novel Controlled-Release Tablet of Pregabalin: Formulation Variation and Pharmacokinetics in Dogs and Humans.

Authors:  Kyung Hun Kim; Seo Hyun Lim; Cho Rok Shim; Junsung Park; Woo Heon Song; Min Chang Kwon; Jong Hyuk Lee; Jun Sang Park; Han-Gon Choi
Journal:  Drug Des Devel Ther       Date:  2020-01-30       Impact factor: 4.162

8.  Design and In-vitro Evaluation of Sustained Release Floating Tablets of Metformin HCl Based on Effervescence and Swelling.

Authors:  Faria Gias Senjoti; Syed Mahmood; Juliana Md Jaffri; Uttam Kumar Mandal
Journal:  Iran J Pharm Res       Date:  2016       Impact factor: 1.696
  8 in total

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