Literature DB >> 24000211

Childhood dermatomyositis recurring in adulthood half a century later.

M Ismajli1, E Nikiphorou, A Young.   

Abstract

A 62-year-old woman presented to the emergency department with malaise, lethargy and proximal muscle weakness. She had a similar presentation in childhood. A muscle biopsy was inconclusive, however, she was treated for a presumptive diagnosis of inflammatory myositis. In a second flare in childhood, she developed proximal muscle weakness and calcinosis cutis. A muscle biopsy was consistent with juvenile dermatomyositis. She was treated with corticosteroids, however, she relapsed again 1 year later, requiring a prolonged course of corticosteroids, which led to remission and treatment was subsequently stopped. She remained well for 30 years without any relapses, however, at the age of 40 she was diagnosed with malignant melanoma, treated with local excision and radiotherapy. She had a further period of 22 years in good health, until her current presentation, with a relapse of dermatomyositis, 52 years after the last flare. She is currently in remission following successful immunosuppressive therapy.

Entities:  

Mesh:

Year:  2013        PMID: 24000211      PMCID: PMC3794143          DOI: 10.1136/bcr-2013-200008

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  9 in total

Review 1.  Menopause, oestrogens and arthritis.

Authors:  A E Wluka; F M Cicuttini; T D Spector
Journal:  Maturitas       Date:  2000-06-30       Impact factor: 4.342

2.  Dermatomyositis: A study of five cases.

Authors:  T D Kinney; M M Maher
Journal:  Am J Pathol       Date:  1940-09       Impact factor: 4.307

Review 3.  Cancer and myositis: new insights into an old association.

Authors:  Stuart M Levine
Journal:  Curr Opin Rheumatol       Date:  2006-11       Impact factor: 5.006

Review 4.  Dermatomyositis and polymyositis: Clinical presentation, autoantibodies, and pathogenesis.

Authors:  Andrew L Mammen
Journal:  Ann N Y Acad Sci       Date:  2010-01       Impact factor: 5.691

Review 5.  [Dermatomyositis in childhood with recurrence in adulthood: 2 cases].

Authors:  B Touton; V Lecerf; B Crickx; C Picard; V Michaud; M H L'Anthoën-Arditi; S Belaïch
Journal:  Ann Dermatol Venereol       Date:  1993       Impact factor: 0.777

6.  Unusual case of childhood dermatomyositis.

Authors:  A Martini; A Ravelli
Journal:  Ann Rheum Dis       Date:  1985-05       Impact factor: 19.103

7.  Medium- and long-term functional outcomes in a multicenter cohort of children with juvenile dermatomyositis.

Authors:  A M Huber; B Lang; C M LeBlanc; N Birdi; R K Bolaria; P Malleson; I MacNeil; J A Momy; G Avery; B M Feldman
Journal:  Arthritis Rheum       Date:  2000-03

8.  Enhanced autoantigen expression in regenerating muscle cells in idiopathic inflammatory myopathy.

Authors:  Livia Casciola-Rosen; Kanneboyina Nagaraju; Paul Plotz; Kondi Wang; Stuart Levine; Edward Gabrielson; Andrea Corse; Antony Rosen
Journal:  J Exp Med       Date:  2005-02-21       Impact factor: 14.307

Review 9.  Why are women predisposed to autoimmune rheumatic diseases?

Authors:  Jacqueline E Oliver; Alan J Silman
Journal:  Arthritis Res Ther       Date:  2009-10-26       Impact factor: 5.156

  9 in total

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