Michael Laxy1, Rolf Holle, Angela Döring, Annette Peters, Matthias Hunger. 1. Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Health Economics and Health Care Management, Neuherberg, Germany, michael.laxy@helmholtz-muenchen.de.
Abstract
OBJECTIVES: Despite the increasing importance of patient-centered perspectives, the impact of weight change on the health-related quality of life (HRQL) has remained unclear. This work aims to investigate this longitudinal relationship. METHODS: Data was collected from a population-based cohort study of 3,080 Germans. Anthropometrics and HRQL were assessed at baseline and after a 7-year follow-up period. Using linear regression the average change in HRQL scores was calculated among 5 mutually exclusive weight change groups. Multilevel growth modeling was conducted to differentiate between interpersonal (cross-sectional) and intrapersonal (longitudinal) associations between body mass index (BMI)/BMI change and HRQL. RESULTS: Heavy weight gain (≥10 % body weight) was associated with impairments in physical health among women (-2.82 points, CI: -4.29, -1.34) and obese men (-4.33 points, CI: -7.62, -1.04) and with improvements in mental health among women (+3.20 points, CI: +1.37, +5.02). Results from the multilevel models were consistent, showing negative associations between BMI change and physical health, positive associations between BMI change and mental health and a high degree of similarity between interpersonal and intrapersonal associations. CONCLUSIONS: Weight gain leads to clinically relevant impairments in physical health. More research is needed to clarify the antipodal effects of weight change on physical and mental health components.
OBJECTIVES: Despite the increasing importance of patient-centered perspectives, the impact of weight change on the health-related quality of life (HRQL) has remained unclear. This work aims to investigate this longitudinal relationship. METHODS: Data was collected from a population-based cohort study of 3,080 Germans. Anthropometrics and HRQL were assessed at baseline and after a 7-year follow-up period. Using linear regression the average change in HRQL scores was calculated among 5 mutually exclusive weight change groups. Multilevel growth modeling was conducted to differentiate between interpersonal (cross-sectional) and intrapersonal (longitudinal) associations between body mass index (BMI)/BMI change and HRQL. RESULTS: Heavy weight gain (≥10 % body weight) was associated with impairments in physical health among women (-2.82 points, CI: -4.29, -1.34) and obesemen (-4.33 points, CI: -7.62, -1.04) and with improvements in mental health among women (+3.20 points, CI: +1.37, +5.02). Results from the multilevel models were consistent, showing negative associations between BMI change and physical health, positive associations between BMI change and mental health and a high degree of similarity between interpersonal and intrapersonal associations. CONCLUSIONS:Weight gain leads to clinically relevant impairments in physical health. More research is needed to clarify the antipodal effects of weight change on physical and mental health components.
Authors: Saskia P J Verkleij; Marcel C Adriaanse; Gerrie C W Wendel-Vos; Albertine J Schuit Journal: Eur J Public Health Date: 2012-05-29 Impact factor: 3.367
Authors: Rochelle E Garner; David H Feeny; Amanda Thompson; Julie Bernier; Bentson H McFarland; Nathalie Huguet; Mark S Kaplan; Heather Orpana; Nancy A Ross; Chris Blanchard Journal: Qual Life Res Date: 2011-08-13 Impact factor: 4.147
Authors: Jordi Alonso; Montserrat Ferrer; Barbara Gandek; John E Ware; Neil K Aaronson; Paola Mosconi; Niels K Rasmussen; Monika Bullinger; Shunichi Fukuhara; Stein Kaasa; Alain Leplège Journal: Qual Life Res Date: 2004-03 Impact factor: 4.147
Authors: Wilma M Hopman; Claudie Berger; Lawrence Joseph; Susan I Barr; Yongjun Gao; Jerilynn C Prior; Suzette Poliquin; Tanveer Towheed; Tassos Anastassiades Journal: Qual Life Res Date: 2007-10-24 Impact factor: 4.147
Authors: Milo A Puhan; Alka Ahuja; Mark L Van Natta; Lori E Ackatz; Curtis Meinert Journal: Health Qual Life Outcomes Date: 2011-05-10 Impact factor: 3.186
Authors: M Haftenberger; G B M Mensink; B Herzog; A Kluttig; K H Greiser; B Merz; U Nöthlings; S Schlesinger; S Vogt; B Thorand; A Peters; T Ittermann; H Völzke; S Schipf; J Neamat-Allah; T Kühn; R Kaaks; H Boeing; U Bachlechner; C Scheidt-Nave; A Schienkiewitz Journal: Eur J Clin Nutr Date: 2015-10-28 Impact factor: 4.016
Authors: Rebecca A Jones; Emma R Lawlor; Jack M Birch; Manal I Patel; André O Werneck; Erin Hoare; Simon J Griffin; Esther M F van Sluijs; Stephen J Sharp; Amy L Ahern Journal: Obes Rev Date: 2020-10-25 Impact factor: 9.213
Authors: Anna Svärd; Jouni Lahti; Eira Roos; Ossi Rahkonen; Eero Lahelma; Tea Lallukka; Minna Mänty Journal: BMC Public Health Date: 2017-09-26 Impact factor: 3.295