Literature DB >> 23999169

MEX-3 proteins: recent insights on novel post-transcriptional regulators.

Bruno Pereira1, Mailys Le Borgne, Nicolas T Chartier, Marc Billaud, Raquel Almeida.   

Abstract

RNA-binding proteins of the evolutionarily-conserved MEX-3 family are mediators of post-transcriptional regulation in different organisms. Recent studies highlight their involvement in diverse physiological settings, including the maintenance of a balance between stem cell self-renewal and differentiation. Here, we draw attention to their putative role in tissue homeostasis and disease, particularly cancer.
Copyright © 2013 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  CDX2; MEX-3; RNA-binding protein; carcinogenesis; development; post-transcriptional regulation

Mesh：

Substances：

Year:  2013        PMID： 23999169     DOI： 10.1016/j.tibs.2013.08.004

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  17 in total

1.  Translatome analysis at the egg-to-embryo transition in sea urchin.

Authors:  Héloïse Chassé; Julie Aubert; Sandrine Boulben; Gildas Le Corguillé; Erwan Corre; Patrick Cormier; Julia Morales
Journal:  Nucleic Acids Res       Date:  2018-05-18       Impact factor: 16.971

2.  MEX3A promotes the malignant progression of ovarian cancer by regulating intron retention in TIMELESS.

Authors:  Fangfang Li; Chen Zhao; Yuchao Diao; Zixiang Wang; Jiali Peng; Ning Yang; Chunping Qiu; Beihua Kong; Yingwei Li
Journal:  Cell Death Dis       Date:  2022-06-17       Impact factor: 9.685

3.  Pivotal role of RNA-binding E3 ubiquitin ligase MEX3C in RIG-I-mediated antiviral innate immunity.

Authors:  Kanako Kuniyoshi; Osamu Takeuchi; Surya Pandey; Takashi Satoh; Hidenori Iwasaki; Shizuo Akira; Taro Kawai
Journal:  Proc Natl Acad Sci U S A       Date:  2014-03-27       Impact factor: 11.205

4.  Interaction profiling of RNA-binding ubiquitin ligases reveals a link between posttranscriptional regulation and the ubiquitin system.

Authors:  Andrea Hildebrandt; Gregorio Alanis-Lobato; Andrea Voigt; Kathi Zarnack; Miguel A Andrade-Navarro; Petra Beli; Julian König
Journal:  Sci Rep       Date:  2017-11-29       Impact factor: 4.379

5.  Structural and functional characterization of hMEX-3C Ring finger domain as an E3 ubiquitin ligase.

Authors:  Sayed Ala Moududee; Yiyang Jiang; Nshogoza Gilbert; Guodong Xie; Zheng Xu; Jihui Wu; Qingguo Gong; Yajun Tang; Yunyu Shi
Journal:  Protein Sci       Date:  2018-09       Impact factor: 6.725

6.  Comprehensive Analysis of Prognostic Value of MEX3A and Its Relationship with Immune Infiltrates in Ovarian Cancer.

Authors:  Panpan Zhang; Tong Su; Shu Zhang
Journal:  J Immunol Res       Date:  2021-06-03       Impact factor: 4.818

Review 7.  Oncogenic Potential of the Dual-Function Protein MEX3A.

Authors:  Marcell Lederer; Simon Müller; Markus Glaß; Nadine Bley; Christian Ihling; Andrea Sinz; Stefan Hüttelmaier
Journal:  Biology (Basel)       Date:  2021-05-07

8.  The RNA-binding protein Mex3B is a coreceptor of Toll-like receptor 3 in innate antiviral response.

Authors:  Yan Yang; Su-Yun Wang; Zhe-Fu Huang; Hong-Mei Zou; Bing-Ru Yan; Wei-Wei Luo; Yan-Yi Wang
Journal:  Cell Res       Date:  2016-01-29       Impact factor: 25.617

9.  Identification of hMex-3A and its effect on human bladder cancer cell proliferation.

Authors:  Ying Huang; Chao Fang; Jing-Wen Shi; Yu Wen; Da Liu
Journal:  Oncotarget       Date:  2017-05-22

10.  The RNA-Binding Ubiquitin Ligase MEX3A Affects Glioblastoma Tumorigenesis by Inducing Ubiquitylation and Degradation of RIG-I.

Authors:  Francesca Bufalieri; Miriam Caimano; Ludovica Lospinoso Severini; Irene Basili; Francesco Paglia; Luigi Sampirisi; Elena Loricchio; Marialaura Petroni; Gianluca Canettieri; Antonio Santoro; Luca D'Angelo; Paola Infante; Lucia Di Marcotullio
Journal:  Cancers (Basel)       Date:  2020-01-30       Impact factor: 6.639
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