Hepatic lipofuscinosis in healthy Norwegian sheep.

Sheep livers with environmental pigmentation were examined histochemically and by electron microscopy. The pigment granules in hepatocytes and Kupffer cells had abundant lipid droplets; they were interpreted as being a variant of lipofuscins. It is concluded that the presently used descriptive term for the condition, "perilobular liver melanosis" should be replaced by the expression "liver lipofuscinosis".