| Literature DB >> 2399812 |
F Slowik1, I Fazekas, K Bálint, L Gazsó, E Pásztor, S Czirják, K Lapis.
Abstract
The histological, ultrastructural and immunocytochemical features are reported of an intrasellar neuronal and lipomatous hamartoma associated with pituitary growth hormone (GH) cell adenoma and acromegaly. Electron microscopy demonstrated a close contact between neurons and adenomatous GH cells. By immunohistochemistry the adenoma cells revealed a positive staining for GH and prolactin. The neurons of hamartoma showed neurosecretory activity which might have induced the development of pituitary GH cell adenoma.Entities:
Mesh:
Year: 1990 PMID: 2399812 DOI: 10.1007/bf00294652
Source DB: PubMed Journal: Acta Neuropathol ISSN: 0001-6322 Impact factor: 17.088