Literature DB >> 23998086

Teratocarcinoma in a non seminomatous, mixed germ cell tumour of the testis-a rare entity.

Gayathri Malavalli1, Shilpa Karra, Bharathi Muniyappa.   

Abstract

Mixed Germ Cell Tumours (MGCTs) of the testis are the second most common testicular tumours. In the 10 years retrospective study which was done on testicular neoplasms at our institute, this reported case accounted for 0.4%. We are presenting the case of a 30 year old male with a painless testicular swelling. Abdominal ultrasonography disclosed it as a seminoma and the FNAC report was Mixed Germ Cell tumour of the testis. Histopathology concurred the cytological diagnosis and it additionally revealed the concomitant presence of a Yolk Sac Tumour (YST) and a Teratocarcinoma in a Non-Seminomatous Tumour of the testis. This case attains uniqueness with the very rare presence of the yolk sac tumour with the teratocarcinoma component in Non-Seminomatous Testicular Tumours. The reason behind the reporting of the case was its poor therapeutic response.

Entities:  

Keywords:  MGCT; Non seminomatous testicular tumour; Teratocarcinoma; YST

Year:  2013        PMID: 23998086      PMCID: PMC3749656          DOI: 10.7860/JCDR/2013/5404.3161

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  6 in total

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Journal:  Cancer       Date:  1995-05-01       Impact factor: 6.860

4.  Malignant transformation of testicular teratoma: a chemoresistant phenotype.

Authors:  Philippe E Spiess; Louis L Pisters; Ping Liu; Curtis A Pettaway; Ashish M Kamat; Jose A Gomez; Nizar M Tannir
Journal:  Urol Oncol       Date:  2008-01-14       Impact factor: 3.498

5.  Histology in mixed germ cell tumors. Is there a favorite pairing?

Authors:  Ashraf A Mosharafa; Richard S Foster; Bradley C Leibovich; Thomas M Ulbright; Richard Bihrle; Lawrence H Einhorn; John P Donohue
Journal:  J Urol       Date:  2004-04       Impact factor: 7.450

6.  Chemotherapy for teratoma with malignant transformation.

Authors:  Alessia C Donadio; Robert J Motzer; Dean F Bajorin; Philip W Kantoff; Joel Sheinfeld; Jane Houldsworth; Raju S K Chaganti; George J Bosl
Journal:  J Clin Oncol       Date:  2003-12-01       Impact factor: 44.544

  6 in total
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1.  The HERV-K accessory protein Np9 controls viability and migration of teratocarcinoma cells.

Authors:  Susana M Chan; Tamar Sapir; Sung-Soo Park; Jean-François Rual; Rafael Contreras-Galindo; Orly Reiner; David M Markovitz
Journal:  PLoS One       Date:  2019-02-28       Impact factor: 3.240

  1 in total

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