Literature DB >> 23997517

Profile of oral squamous cell cancer in a tertiary level medical college hospital: a 10 yr study.

Raj Govind Sharma1, Bhavesh Bang, Hemlata Verma, J M Mehta.   

Abstract

To know the clinical and epidemiological characteristics & management strategies for the patients who underwent surgery for oral Squamous Cell Cancer (SCC) in a medical college hospital. Data pertaining to clinico-epidemiological factors & surgical management for oral cancer were analyzed in patients admitted to a tertiary level medical college hospital. Records of 139 patients admitted over a period of 10 years (January 1998 to December 2007) were used for data analysis. Only patients with complete records were included in the analysis. M: F ratio was 2.2:1 with average age of patients being 50.4 years. Tobacco chewing & smoking were major predisposing factors identified. Oral ulcer was the most common symptom while buccal mucosa, tongue & lower alveolus were three most common primary tumor sites. Majority of tumors were stage IV at presentation (52 %). Wide excision of tumor was done in 46 % of cases while in 54 % cases commando procedure was done. Reconstruction after either commando or wide excision was done in half of the patients. Pectoralis major myocutaneous (PMMC) flap was used in majority of cases for reconstruction. Neck dissection was done in 67 % patients. Majority (85 %) of these were radical neck dissection (RND). Per operative blood transfusions were required in 64 % patients while 19 % patients needed post operative transfusion. Post operative complications were noted in 34 % of the patients. Of these majority were related to wound infection & orocutaneous fistula formation. Hospital stay varied from 7 to 105 days with the mean duration of 30 days. Two year follow up revealed a recurrence rate of 36 %. Majority of the patients presented at an advanced stage due to self as well as professional delay in diagnosis. This leads to difficulty in resection of the primary tumor as well as reconstruction of the defect. A higher rate of recurrence after surgery is also seen. Post operative complications increase the morbidity which is reflected by an increase in the hospital stay (19 days Vs 46 days).

Entities:  

Keywords:  Epidemiology; Oral cancer; Tobacco

Year:  2012        PMID: 23997517      PMCID: PMC3444586          DOI: 10.1007/s13193-012-0165-z

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  17 in total

1.  Risk factors for postoperative complications in oral cancer and their prognostic implications.

Authors:  G M de Melo; K C Ribeiro ; L P Kowalski; D Deheinzelin
Journal:  Arch Otolaryngol Head Neck Surg       Date:  2001-07

2.  Simultaneous reconstruction of large skin and mucosal defect following head and neck surgery with a single skin paddle pectoralis major myocutaneous flap.

Authors:  P Chaturvedi; P S Pai; K A Pathak; D A Chaukar; M S Deshpande; A K D'Cruz
Journal:  J Laryngol Otol       Date:  2005-04       Impact factor: 1.469

3.  Pattern of lymphatic spread from carcinoma of the buccal mucosa and its implication for less than radical surgery.

Authors:  Manoj Pandey; Mridula Shukla; C S Nithya
Journal:  J Oral Maxillofac Surg       Date:  2010-08-03       Impact factor: 1.895

4.  Autologous and heterologous blood transfusion in head and neck cancer surgery.

Authors:  M S Moir; R N Samy; M M Hanasono; D J Terris
Journal:  Arch Otolaryngol Head Neck Surg       Date:  1999-08

5.  Squamous cell carcinoma of the gingivobuccal complex: predictors of locoregional failure in stage III-IV cancers.

Authors:  Rohan R Walvekar; Devendra A Chaukar; Mandar S Deshpande; Prathamesh S Pai; Pankaj Chaturvedi; Anagha Kakade; Anil K D'Cruz
Journal:  Oral Oncol       Date:  2008-07-14       Impact factor: 5.337

6.  Oral cancers in Mumbai, India: a fifteen years perspective with respect to incidence trend and cumulative risk.

Authors:  Lizzy Sunny; B B Yeole; M Hakama; R Shiri; P S R K Sastry; S Mathews; S H Advani
Journal:  Asian Pac J Cancer Prev       Date:  2004 Jul-Sep

7.  Reassessment of risk factors for oral cancer.

Authors:  Nitin Gangane; Shweta Chawla; Anshu Subodh; Subodh Sharan Gupta; Satish M Sharma
Journal:  Asian Pac J Cancer Prev       Date:  2007 Apr-Jun

8.  Reconstruction of complex oral defects using bi-paddle pectoralis major flap - technical modifications and outcome in 54 cancer patients.

Authors:  S V S Deo; Joydeep Purkayastha; Diganta Kr Das; Madhabananda Kar; Guddanti Srinivas; Sonal Asthana; Shridhar D; N K Shukla
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2003-03

9.  Spectrum of Head-Neck cancers at Allahabad.

Authors:  H Ahluwalia; S C Gupta; M Singh; S C Gupta; V Mishra; P A Singh; D K Walia
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2001-01

10.  Clinical and epidemiological features of oral cancer in a medical school teaching hospital from 1994 to 2002: increasing incidence in women, predominance of advanced local disease, and low incidence of neck metastases.

Authors:  Marcelo D Durazzo; Carlos Eugenio Nabuco de Araujo; José de Souza Brandão Neto; André de Souza Potenza; Pedro Costa; Flávio Takeda; Cristina Bianchi; Marcos R Tavares; Gilberto de Britto e Silva Filho; Alberto R Ferraz
Journal:  Clinics (Sao Paulo)       Date:  2005-08-29       Impact factor: 2.365

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  2 in total

Review 1.  Oral Field Cancerization and Its Clinical Implications in the Management in Potentially Malignant Disorders.

Authors:  Anisha Cynthia Sathiasekar; Deepu George Mathew; M S Jaish Lal; A A Arul Prakash; K U Goma Kumar
Journal:  J Pharm Bioallied Sci       Date:  2017-11

2.  Prevalence of oral cancer and oral epithelial dysplasia among North Indian population: A retrospective institutional study.

Authors:  Shruti Singh; Jaya Singh; Shaleen Chandra; Fahad Mansoor Samadi
Journal:  J Oral Maxillofac Pathol       Date:  2020-05-08
  2 in total

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