Literature DB >> 23996830

Polymer nanoparticles for drug and small silencing RNA delivery to treat cancers of different phenotypes.

Rammohan Devulapally1, Ramasamy Paulmurugan.   

Abstract

Advances in nanotechnology have provided powerful and efficient tools in the development of cancer diagnosis and therapy. There are numerous nanocarriers that are currently approved for clinical use in cancer therapy. In recent years, biodegradable polymer nanoparticles have attracted a considerable attention for their ability to function as a possible carrier for target-specific delivery of various drugs, genes, proteins, peptides, vaccines, and other biomolecules in humans without much toxicity. This review will specifically focus on the recent advances in polymer-based nanocarriers for various drugs and small silencing RNA's loading and delivery to treat different types of cancer.
© 2013 Wiley Periodicals, Inc.

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Year:  2013        PMID： 23996830      PMCID： PMC3865230          DOI： 10.1002/wnan.1242

Source DB:  PubMed          Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol        ISSN： 1939-0041


  103 in total

Review 1.  Strategies for silencing human disease using RNA interference.

Authors:  Daniel H Kim; John J Rossi
Journal:  Nat Rev Genet       Date:  2007-03       Impact factor: 53.242

2.  Characterization of cisplatin cytotoxicity delivered from PLGA-systems.

Authors:  Daniel Moreno; Conchita Tros de Ilarduya; Eva Bandrés; María Buñuales; María Azcona; Jesús García-Foncillas; María J Garrido
Journal:  Eur J Pharm Biopharm       Date:  2007-08-08       Impact factor: 5.571

3.  Formulation, characterization and evaluation of curcumin-loaded PLGA nanospheres for cancer therapy.

Authors:  Anindita Mukerjee; Jamboor K Vishwanatha
Journal:  Anticancer Res       Date:  2009-10       Impact factor: 2.480

4.  Preparation, physicochemical characterization and cytotoxicity in vitro of gemcitabine-loaded PEG-PDLLA nanovesicles.

Authors:  Lin Jia; Jian-Jun Zheng; Shu-Man Jiang; Kai-Hong Huang
Journal:  World J Gastroenterol       Date:  2010-02-28       Impact factor: 5.742

5.  Tamoxifen-loaded nanoparticles based on a novel mixture of biodegradable polyesters: characterization and in vitro evaluation as sustained release systems.

Authors:  Elena Pérez; Marta Benito; César Teijón; Rosa Olmo; José M Teijón; M Dolores Blanco
Journal:  J Microencapsul       Date:  2012-01-18       Impact factor: 3.142

Review 6.  Nanoparticles for drug delivery in cancer treatment.

Authors:  Barbara Haley; Eugene Frenkel
Journal:  Urol Oncol       Date:  2008 Jan-Feb       Impact factor: 3.498

7.  Interfering nanoparticles for silencing microRNAs.

Authors:  Huricha Baigude; Tariq M Rana
Journal:  Methods Enzymol       Date:  2012       Impact factor: 1.600

8.  Biodegradable nanoparticles of mPEG-PLGA-PLL triblock copolymers as novel non-viral vectors for improving siRNA delivery and gene silencing.

Authors:  Jing Du; Ying Sun; Qiu-Sheng Shi; Pei-Feng Liu; Ming-Jie Zhu; Chun-Hui Wang; Lian-Fang Du; You-Rong Duan
Journal:  Int J Mol Sci       Date:  2012-01-04       Impact factor: 6.208

Review 9.  Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles.

Authors:  Günter Oberdörster; Eva Oberdörster; Jan Oberdörster
Journal:  Environ Health Perspect       Date:  2005-07       Impact factor: 9.031

10.  5-Fluorouracil nanoparticles inhibit hepatocellular carcinoma via activation of the p53 pathway in the orthotopic transplant mouse model.

Authors:  Mingrong Cheng; Bing He; Tao Wan; Weiping Zhu; Jiang Han; Bingbing Zha; Houxiang Chen; Fengxiao Yang; Qing Li; Wei Wang; Hongzhi Xu; Tao Ye
Journal:  PLoS One       Date:  2012-10-15       Impact factor: 3.240
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  22 in total

1.  Ultrasound-guided delivery of thymidine kinase-nitroreductase dual therapeutic genes by PEGylated-PLGA/PIE nanoparticles for enhanced triple negative breast cancer therapy.

Authors:  Rammohan Devulapally; Taehwa Lee; Aarohi Barghava-Shah; Thillai V Sekar; Kira Foygel; Sunitha V Bachawal; Jürgen K Willmann; Ramasamy Paulmurugan
Journal:  Nanomedicine (Lond)       Date:  2018-05-23       Impact factor: 5.307

2.  Ultrasound/microbubble-mediated targeted delivery of anticancer microRNA-loaded nanoparticles to deep tissues in pigs.

Authors:  Tommaso Di Ianni; Rajendran J C Bose; Uday K Sukumar; Sunitha Bachawal; Huaijun Wang; Arsenii Telichko; Carl Herickhoff; Elise Robinson; Sam Baker; José G Vilches-Moure; Stephen A Felt; Sanjiv S Gambhir; Ramasamy Paulmurugan; Jeremy D Dahl
Journal:  J Control Release       Date:  2019-07-18       Impact factor: 9.776

Review 3.  Nanotechnology in radiation oncology.

Authors:  Andrew Z Wang; Joel E Tepper
Journal:  J Clin Oncol       Date:  2014-08-11       Impact factor: 44.544

4.  Ultrasound-guided delivery of microRNA loaded nanoparticles into cancer.

Authors:  Tzu-Yin Wang; Jung Woo Choe; Kanyi Pu; Rammohan Devulapally; Sunitha Bachawal; Steven Machtaler; Sayan Mullick Chowdhury; Richard Luong; Lu Tian; Butrus Khuri-Yakub; Jianghong Rao; Ramasamy Paulmurugan; Jürgen K Willmann
Journal:  J Control Release       Date:  2015-02-14       Impact factor: 9.776

5.  Orlistat and antisense-miRNA-loaded PLGA-PEG nanoparticles for enhanced triple negative breast cancer therapy.

Authors:  Aarohi Bhargava-Shah; Kira Foygel; Rammohan Devulapally; Ramasamy Paulmurugan
Journal:  Nanomedicine (Lond)       Date:  2016-01-20       Impact factor: 5.307

6.  BRET Sensors for Imaging Membrane Integrity of Microfluidically Generated Extracellular Vesicles.

Authors:  Ramasamy Paulmurugan; Yi Liu; Uday Kumar Sukumar; Masamitsu Kanada; Tarik F Massoud
Journal:  Methods Mol Biol       Date:  2022

7.  Intracellular MicroRNA Quantification in Intact Cells: A Novel Strategy based on Reduced Graphene Oxide Based Fluorescence Quenching.

Authors:  Ramasamy Paulmurugan; Pulickel M Ajayan; Dorian Liepmann; V Renugopalakrishnan
Journal:  MRS Commun       Date:  2018-07-13       Impact factor: 2.566

8.  Gemcitabine and Antisense-microRNA Co-encapsulated PLGA-PEG Polymer Nanoparticles for Hepatocellular Carcinoma Therapy.

Authors:  Rammohan Devulapally; Kira Foygel; Thillai V Sekar; Juergen K Willmann; Ramasamy Paulmurugan
Journal:  ACS Appl Mater Interfaces       Date:  2016-12-02       Impact factor: 9.229

Review 9.  Nanomedicines for kidney diseases.

Authors:  Ryan M Williams; Edgar A Jaimes; Daniel A Heller
Journal:  Kidney Int       Date:  2016-06-09       Impact factor: 10.612

10.  Folate Receptor-Targeted Polymeric Micellar Nanocarriers for Delivery of Orlistat as a Repurposed Drug against Triple-Negative Breast Cancer.

Authors:  Ramasamy Paulmurugan; Rohith Bhethanabotla; Kaushik Mishra; Rammohan Devulapally; Kira Foygel; Thillai V Sekar; Jeyarama S Ananta; Tarik F Massoud; Abraham Joy
Journal:  Mol Cancer Ther       Date:  2015-11-09       Impact factor: 6.261
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