Flávia Mauad Levy1, Daniela Rios2, Marília A R Buzalaf1, Ana Carolina Magalhães3. 1. Department of Biological Sciences, University of São Paulo, Al. Dr. Octávio Pinheiro Brisolla, 9-75, Bauru, SP, 17012-901, Brazil. 2. Department of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, Al. Dr. Octávio Pinheiro Brisolla, 9-75, Bauru, SP, 17012-901, Brazil. 3. Department of Biological Sciences, University of São Paulo, Al. Dr. Octávio Pinheiro Brisolla, 9-75, Bauru, SP, 17012-901, Brazil. acm@fob.usp.br.
Abstract
OBJECTIVES: This in situ/ex vivo study analysed the anti-erosive/abrasive effect of TiF4 and NaF varnish and solution on enamel wear. MATERIALS AND METHODS: Twelve subjects took part in this study which was performed in three periods (phases) with the duration of 5 days each. Each two human enamel specimens per subject were pretreated with experimental NaF varnish or solution (phase A), experimental-TiF4 varnish or solution (phase B) and placebo varnish or untreated control (phase C). The specimens were worn in palatal appliances; one enamel specimen, from each treatment, was subjected to erosion (ERO; cola soft drink, 4 × 90 s/day), and the other specimen was subjected to erosion plus abrasion (ERO + ABR; tooth brushing, 2 × 10 s/day). The tooth wear was quantified by a contact profilometer (micrometre) and analysed using two-way repeated measures ANOVA and Bonferroni's test (n = 12 subjects, p < 0.05). RESULTS: All fluoride varnishes and solutions reduced the enamel wear (around 25 %) significantly compared to the control and placebo varnish. There were no significant differences among the fluoride formulations and between the conditions ERO and ERO + ABR. CONCLUSIONS: Therefore, it can be concluded that TiF4 has the same protective potential as NaF formulations to reduce human enamel wear under this experimental in situ model. CLINICAL SIGNIFICANCE: In vitro studies have indicated a better anti-erosive/abrasive effect of TiF4 compared to NaF varnish. The present in situ study does not support the previous findings. Therefore, any of the tested professional fluoride varnishes in principle could be able to partially reduce enamel wear.
RCT Entities:
OBJECTIVES: This in situ/ex vivo study analysed the anti-erosive/abrasive effect of TiF4 and NaF varnish and solution on enamel wear. MATERIALS AND METHODS: Twelve subjects took part in this study which was performed in three periods (phases) with the duration of 5 days each. Each two human enamel specimens per subject were pretreated with experimental NaF varnish or solution (phase A), experimental-TiF4 varnish or solution (phase B) and placebo varnish or untreated control (phase C). The specimens were worn in palatal appliances; one enamel specimen, from each treatment, was subjected to erosion (ERO; cola soft drink, 4 × 90 s/day), and the other specimen was subjected to erosion plus abrasion (ERO + ABR; tooth brushing, 2 × 10 s/day). The tooth wear was quantified by a contact profilometer (micrometre) and analysed using two-way repeated measures ANOVA and Bonferroni's test (n = 12 subjects, p < 0.05). RESULTS: All fluoride varnishes and solutions reduced the enamel wear (around 25 %) significantly compared to the control and placebo varnish. There were no significant differences among the fluoride formulations and between the conditions ERO and ERO + ABR. CONCLUSIONS: Therefore, it can be concluded that TiF4 has the same protective potential as NaF formulations to reduce human enamel wear under this experimental in situ model. CLINICAL SIGNIFICANCE: In vitro studies have indicated a better anti-erosive/abrasive effect of TiF4 compared to NaF varnish. The present in situ study does not support the previous findings. Therefore, any of the tested professional fluoride varnishes in principle could be able to partially reduce enamel wear.
Authors: Livia P Comar; Annette Wiegand; Bruna M Moron; Daniela Rios; Marília A R Buzalaf; Wolfgang Buchalla; Ana C Magalhães Journal: Eur J Oral Sci Date: 2012-06-25 Impact factor: 2.612
Authors: A Lussi; M A R Buzalaf; D Duangthip; V Anttonen; C Ganss; S H João-Souza; T Baumann; T S Carvalho Journal: Eur Arch Paediatr Dent Date: 2019-02-14
Authors: Kelly Polido Kaneshiro Olympio; Manuel Fernando Gonzalez Huila; Cristiane de Almeida Baldini Cardoso; Ana Paula Sacone da Silva Ferreira; Adrielly Garcia Ortiz; Henrique Eisi Toma; Ricardo Henrique Alves da Silva; Maciel Santos Luz; Maria Regina Alves Cardoso; Gislayne Aparecida Rodrigues Kelmer; Pedro Vitoriano de Oliveira; Etelvino José Henriques Bechara; Wanda Maria Risso Günther; Marília Afonso Rabelo Buzalaf Journal: Environ Sci Pollut Res Int Date: 2017-12-20 Impact factor: 4.223