Literature DB >> 23996326

Carbon nanodots featuring efficient FRET for real-time monitoring of drug delivery and two-photon imaging.

Jing Tang1, Biao Kong, Hao Wu, Ming Xu, Yongcheng Wang, Yanli Wang, Dongyuan Zhao, Gengfeng Zheng.   

Abstract

A FRET-based carbon nanodot (CDot) drug delivery platform has been developed. These CDots offer excellent biocompatibility, stable fluorescence, and efficient FRET between CDots and the attached fluorescent drug molecules, such as doxorubicin, enabling enhanced drug delivery, convenient cell imaging, and real-time monitoring of drug release. Moreover, the FRET-based two-photon imaging and drug tracking in deep tissues are also demonstrated.
© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  FRET; carbon nanodots; cytotoxicity; drug delivery; monitoring; two-photon imaging

Mesh:

Substances:

Year:  2013        PMID: 23996326     DOI: 10.1002/adma.201303124

Source DB:  PubMed          Journal:  Adv Mater        ISSN: 0935-9648            Impact factor:   30.849


  50 in total

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