| Literature DB >> 23995069 |
Francesca Viganò1, Wiebke Möbius, Magdalena Götz, Leda Dimou.
Abstract
To examine the role of gray and white matter niches for oligodendrocyte differentiation, we used homo- and heterotopic transplantations into the adult mouse cerebral cortex. White matter-derived cells differentiated into mature oligodendrocytes in both niches with equal efficiency, whereas gray matter-derived cells did not. Thus, white matter promotes oligodendrocyte differentiation, and cells from this niche differentiate more easily, even in the less supportive gray matter environment.Entities:
Mesh：
Year: 2013 PMID： 23995069 DOI： 10.1038/nn.3503
Source DB: PubMed Journal: Nat Neurosci ISSN： 1097-6256 Impact factor: 24.884