| Literature DB >> 23994232 |
Mi Zhang1, Junsong Wang1, Jun Luo1, Pengran Wang1, Chao Guo1, Lingyi Kong2.
Abstract
Five new labdane diterpenes (1-5), serralabdanes A-E, were isolated from the whole plant of Chloranthus serratus. Their structures were elucidated by spectroscopic methods, and the absolute configuration of the 12,13-diol moiety in serralabdane C (3) was determined by observing the induced circular dichroism (ICD) after addition of dimolybdenum teracetate in DMSO solution. Serralabdanes A-E (1-5) showed inhibitory effects on lipopolysaccharide-induced nitric oxide production in RAW264.7 cells.Entities:
Keywords: Anti-inflammatory; Chloranthus serratus; Induced circular dichroism; Labdane diterpene
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Year: 2013 PMID: 23994232 DOI: 10.1016/j.fitote.2013.08.015
Source DB: PubMed Journal: Fitoterapia ISSN: 0367-326X Impact factor: 2.882