Yiftach Roth1, Gaby S Pell2, Andrei V Chistyakov3, Alon Sinai4, Abraham Zangen2, Menashe Zaaroor3. 1. Department of Life Sciences, Ben-Gurion University, Beer Sheva, Israel. Electronic address: Yiftach@brainsway.com. 2. Department of Life Sciences, Ben-Gurion University, Beer Sheva, Israel. 3. Department of Neurosurgery, Rambam Health Care Campus and B. Rappaport, Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. 4. Department of Neurosurgery, Rambam Health Care Campus, Haifa, Israel; Department of Neurology, Rambam Health Care Campus, Haifa, Israel.
Abstract
OBJECTIVE: To compare the ability of an H-coil and figure-8 coil to stimulate different motor cortex regions. METHODS: The resting (rMT) and active (aMT) motor thresholds were measured for the right hand APB and leg AHB muscles in 10 subjects, using an H-coil and a figure-8 coil. The electric field distribution induced by the coils was measured in a head model. The combination of the hand and leg MTs with the field measurements was used to determine the depth of hand and leg motor areas via the intersection points. RESULTS: The rMT and aMT of both APB and AHB were significantly lower for the H-coil. The ratio and difference between the leg and hand rMT and aMT were significantly lower for the H-Coil. Electric field measurements revealed significantly more favorable depth profile and larger volume of stimulation for the H-coil. The averaged intersection for the APB was at a distance from coil of 1.83±0.54cm and at an intensity of 97.8±21.4V/m, while for the AHB it was at a distance of 2.73±0.44cm and at an intensity of 118.6±21.3V/m. CONCLUSION: The results suggest a more efficient activation of deeper motor cortical regions using the H-coil. SIGNIFICANCE: The combined evaluation of MTs by H- and figure-8 coils allows measurement of the individual depth of different motor cortex regions. This could be helpful for optimizing stimulation parameters for TMS treatment.
OBJECTIVE: To compare the ability of an H-coil and figure-8 coil to stimulate different motor cortex regions. METHODS: The resting (rMT) and active (aMT) motor thresholds were measured for the right hand APB and leg AHB muscles in 10 subjects, using an H-coil and a figure-8 coil. The electric field distribution induced by the coils was measured in a head model. The combination of the hand and leg MTs with the field measurements was used to determine the depth of hand and leg motor areas via the intersection points. RESULTS: The rMT and aMT of both APB and AHB were significantly lower for the H-coil. The ratio and difference between the leg and hand rMT and aMT were significantly lower for the H-Coil. Electric field measurements revealed significantly more favorable depth profile and larger volume of stimulation for the H-coil. The averaged intersection for the APB was at a distance from coil of 1.83±0.54cm and at an intensity of 97.8±21.4V/m, while for the AHB it was at a distance of 2.73±0.44cm and at an intensity of 118.6±21.3V/m. CONCLUSION: The results suggest a more efficient activation of deeper motor cortical regions using the H-coil. SIGNIFICANCE: The combined evaluation of MTs by H- and figure-8 coils allows measurement of the individual depth of different motor cortex regions. This could be helpful for optimizing stimulation parameters for TMS treatment.
Authors: Tyler S Kaster; Zafiris J Daskalakis; Yoshihiro Noda; Yuliya Knyahnytska; Jonathan Downar; Tarek K Rajji; Yechiel Levkovitz; Abraham Zangen; Meryl A Butters; Benoit H Mulsant; Daniel M Blumberger Journal: Neuropsychopharmacology Date: 2018-06-18 Impact factor: 7.853
Authors: F Proessl; M C Canino; M E Beckner; A M Sinnott; S R Eagle; A D LaGoy; W R Conkright; A J Sterczala; C Connaboy; F Ferrarelli; A Germain; B C Nindl; S D Flanagan Journal: Exp Brain Res Date: 2021-02-06 Impact factor: 1.972
Authors: Sergey N Makarov; Janakinadh Yanamadala; Matthew W Piazza; Alex M Helderman; Niang S Thang; Edward H Burnham; Alvaro Pascual-Leone Journal: IEEE Trans Biomed Eng Date: 2015-12-10 Impact factor: 4.538
Authors: Yechiel Levkovitz; Moshe Isserles; Frank Padberg; Sarah H Lisanby; Alexander Bystritsky; Guohua Xia; Aron Tendler; Zafiris J Daskalakis; Jaron L Winston; Pinhas Dannon; Hisham M Hafez; Irving M Reti; Oscar G Morales; Thomas E Schlaepfer; Eric Hollander; Joshua A Berman; Mustafa M Husain; Uzi Sofer; Ahava Stein; Shmulik Adler; Lisa Deutsch; Frederic Deutsch; Yiftach Roth; Mark S George; Abraham Zangen Journal: World Psychiatry Date: 2015-02 Impact factor: 49.548
Authors: Carolin Weiss; Irada Tursunova; Volker Neuschmelting; Hannah Lockau; Charlotte Nettekoven; Ana-Maria Oros-Peusquens; Gabriele Stoffels; Anne K Rehme; Andrea Maria Faymonville; N Jon Shah; Karl Josef Langen; Roland Goldbrunner; Christian Grefkes Journal: Neuroimage Clin Date: 2015-01-20 Impact factor: 4.881